Evidence map›Paper›PMID 29954414›Full record

ArticleItalian journal of pediatrics2018

Mortality rate of patients with cystic fibrosis on the waiting list and within one year after lung transplantation: a survey of Italian CF centers.

Beatrice Borchi, Marisol Barao Ocampo, Giuseppe Cimino, Giovanna Pizzamiglio, Silvia Bresci, Cesare Braggion, Italian Cystic Fibrosis Lung Transplantation Group

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Italian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Beatrice BorchiInfectious Diseases Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134, Florence, Italy.
Marisol Barao OcampoCystic Fibrosis Center, Azienda Ospedaliero-Universitaria di Verona, P.le Stefani 1, 37126, Verona, Italy.
Giuseppe CiminoCystic Fibrosis Center - Adult Unit, Department of Medicine and Infectious Diseases, University Umberto I, Viale Regina Elena 324, 00161, Rome, Italy.
Giovanna PizzamiglioCystic Fibrosis Center - Adult Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122, Milan, Italy.
Silvia BresciInfectious Diseases Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134, Florence, Italy.
Cesare BraggionCystic Fibrosis Center, Meyer Children's Hospital, Viale Pieraccini 24, 50139, Florence, Italy. cesare.braggion@meyer.it.ORCID http://orcid.org/0000-0002-9241-8943
Italian Cystic Fibrosis Lung Transplantation Group
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITMeyer Children's Hospital · ITAzienda Ospedaliera Universitaria Integrata Verona · ITAzienda Ospedaliero-Universitaria Careggi · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCystic Fibrosis (CF) Centers are involved in the decisions regarding the eligibility of CF patients with end-stage lung disease and timing for inclusion on waiting lists (WL) for lung transplantation (LT). There are currently no data on the mortality rates of Italian CF patients on WL and during the first year after LT and we aimed to assess these outcomes by surveying the CF Centers.

methodsA survey was sent to Italian CF Centers which were requested to report the age at which all CF subjects included on the WL between 2010 and 2014 were included on the list, admitted to either standard or urgent LT, or had died either while on the WL or within the first 3 and 12 months after LT. All outcomes were recorded by December 31, 2015.

resultsTwo hundred fifty-nine CF subjects were included on the WL during the 5-year study period. The mortality rate during the WL was 19.3% and was not associated with sex, age at inclusion on the WL or standard or urgent access to LT. 159 (61.4%) subjects underwent LT, 46 (28.9%) with urgent procedure. Deaths within the first 3 and 12 months after LT were significantly more prevalent in individuals who underwent urgent LT compared to those with standard LT (p < 0.01).

conclusionsThe mortality of Italian CF patients, included in our survey, was about twice that reported by the National Transplant Center for all LT indications, including CF, during the same time period and despite the introduction of urgent LT. The latter was associated with an unfavorable early outcome compared to standard LT.

Indexed as

Lung TransplantationRegistriesAdultCross-Sectional StudiesCystic FibrosisFemaleHumansIncidenceItalyMaleSurveys and QuestionnairesSurvival RateWaiting ListsYoung Adult

Identifiers

PMID29954414
PMCPMC6022442
OpenAlexW2810744125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.