ArticleBMC pregnancy and childbirth2018
Incidence of postpartum infection, outcomes and associated risk factors at Mbarara regional referral hospital in Uganda.
Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
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43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Burden of Antimicrobial Resistance Among Women with Post-Partum Infections in Low-Middle Income Countries: A Systematic Review.Journal of epidemiology and global health · 2024Pooled it
- Risk factors for postpartum maternal mortality and hospital readmission in low- and middle-income countries: a systematic review.BMC pregnancy and childbirth · 2023Pooled it
- Can Clean Delivery Kits Prevent Infections? Lessons from Traditional Birth Attendants in Nigeria.Annals of global health · 2023Trial
- Trial
- Prevalence and Antimicrobial Susceptibility Patterns of Nosocomial Bacteria across Different Units at King Faisal Complex Hospital, Taif, Kingdom of Saudi Arabia.Saudi medical journal · 2026Article
- Article
- Antimicrobial Consumption and Resistance Dynamics Across Healthcare Level: Global Evidence and Stewardship Implications.Pathogens (Basel, Switzerland) · 2026Review
- Antimicrobial Prescribing Practices for Surgical Prophylaxis in Caesarean Sections at Kawempe National Referral Hospital, Kampala, Uganda.Health science reports · 2026Article
- Impact of repeat cesarean sections on surgical site infections, microbiological patterns, and surgical outcomes: a prospective multicenter cohort study in South Ethiopia.BMC pregnancy and childbirth · 2026Article
- Determinants of puerperal sepsis among postpartum women at public hospital in Gedeo Zone, southern Ethiopia, 2023: unmatched case-control study.BMC pregnancy and childbirth · 2026Article
- Determinants of adequate knowledge of postpartum warning signs and complications among parturients in Ibadan, Nigeria: a cross sectional study.BMC pregnancy and childbirth · 2025Article
- Prevalence and factors associated with puerperal sepsis among postnatal women at a Tertiary Referral Hospital in Western Uganda.PloS one · 2025Article
- Outcomes of a honey and olive oil-based dressing material on wounds of women that have had a caesarean section in south-western Uganda.International wound journal · 2024Article
- Clinical Analysis of Risk Factors and Perinatal Outcomes in Recurrent Pre-Eclampsia with Severe Features.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Impact of postpartum maternal fever or hypothermia on newborn and early infant illness and death in Southwestern Uganda.BMC pregnancy and childbirth · 2024Article
- Reproductive Tract Microbial Transitions from Late Gestation to Early Postpartum Using 16S rRNA Metagenetic Profiling in First-Pregnancy Heifers.International journal of molecular sciences · 2024Article
- Determinants of puerperal sepsis among postpartum women: a case-control study in East Shoa Zone public hospitals, Central Ethiopia.BMJ open · 2024Article
- Inter-facility transfers for emergency obstetrical and neonatal care in rural Madagascar: a cost-effectiveness analysis.BMJ open · 2024Article
- Prevalence of Maternal Fever and Associated Factors among Postnatal Women at Kawempe National Referral Hospital, Uganda: A Preliminary Study.International journal of environmental research and public health · 2024Article
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundThere is a paucity of recent prospective data on the incidence of postpartum infections and associated risk factors in sub-Saharan Africa. Retrospective studies estimate that puerperal sepsis causes approximately 10% of maternal deaths in Africa.
methodsWe enrolled 4231 women presenting to a Ugandan regional referral hospital for delivery or postpartum care into a prospective cohort and measured vital signs postpartum. Women developing fever (> 38.0 °C) or hypothermia (< 36.0 °C) underwent symptom questionnaire, structured physical exam, malaria testing, blood, and urine cultures. Demographic, treatment, and post-discharge outcomes data were collected from febrile/hypothermic women and a random sample of 1708 normothermic women. The primary outcome was in-hospital postpartum infection. Multivariable logistic regression was used to determine factors independently associated with postpartum fever/hypothermia and with confirmed infection.
resultsOverall, 4176/4231 (99%) had ≥1 temperature measured and 205/4231 (5%) were febrile or hypothermic. An additional 1708 normothermic women were randomly selected for additional data collection, for a total sample size of 1913 participants, 1730 (90%) of whom had complete data. The mean age was 25 years, 214 (12%) were HIV-infected, 874 (51%) delivered by cesarean and 662 (38%) were primigravidae. Among febrile/hypothermic participants, 174/205 (85%) underwent full clinical and microbiological evaluation for infection, and an additional 24 (12%) had a partial evaluation. Overall, 84/4231 (2%) of participants met criteria for one or more in-hospital postpartum infections. Endometritis was the most common, identified in 76/193 (39%) of women evaluated clinically. Twenty-five of 175 (14%) participants with urinalysis and urine culture results met criteria for urinary tract infection. Bloodstream infection was diagnosed in 5/185 (3%) participants with blood culture results. Another 5/186 (3%) tested positive for malaria. Cesarean delivery was independently associated with incident, in-hospital postpartum infection (aOR 3.9, 95% CI 1.5-10.3, P = 0.006), while antenatal clinic attendance was associated with reduced odds (aOR 0.4, 95% CI 0.2-0.9, P = 0.02). There was no difference in in-hospital maternal deaths between the febrile/hypothermic (1, 0.5%) and normothermic groups (0, P = 0.11).
conclusionsAmong rural Ugandan women, postpartum infection incidence was low overall, and cesarean delivery was independently associated with postpartum infection while antenatal clinic attendance was protective.
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