Evidence map›Paper›PMID 29954086›Full record

ArticleMolecules (Basel, Switzerland)2018

Antifungal and Cytotoxic Activities of Sixty Commercially-Available Essential Oils.

Chelsea N Powers, Jessica L Osier, Robert L McFeeters, Carolyn Brianne Brazell, Emily L Olsen, Debra M Moriarity, Prabodh Satyal, William N Setzer

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Plants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Sandalwood Sesquiterpene (Molecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Vetiver,Plants (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Saudi journal of biological sciences · 2023
    Article
  10. Antifungal Activity and Type of Interaction ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  11. Co-Delivery of Ylang Ylang Oil ofInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Essential Oils in Respiratory Mycosis: A Review.Molecules (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chelsea N PowersDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. cnp0007@uah.edu.
Jessica L OsierDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. jlo0011@uah.edu.
Robert L McFeetersDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. rlm0004@uah.edu.
Carolyn Brianne BrazellDepartment of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA. cbb0027@uah.edu.
Emily L OlsenDepartment of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA. elo0001@uah.edu.
Debra M MoriarityDepartment of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA. moriard@uah.edu.
Prabodh SatyalAromatic Plant Research Center, 615 St. George Square Court, Suite 300, Winston-Salem, NC 27103, USA. psatyal@aromaticplant.org.
William N SetzerDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. wsetzer@chemistry.uah.edu.ORCID 0000-0002-3639-0528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an urgent and unmet need for new antifungal therapies. Global fungal infection rates continue to rise and fungal infections pose increasing burdens on global healthcare systems. Exacerbating the situation, the available antifungal therapeutic arsenal is limited and development of new antifungals has been slow. Current antifungals are known for unwanted side effects including nephrotoxicity and hepatotoxicity. Thus, the need for new antifungals and new antifungal targets is urgent and growing. A collection of 60 commercially-available essential oils has been screened for antifungal activity against

Indexed as

Antifungal AgentsAspergillusCandida albicansCryptococcus neoformansGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsOils, VolatilePlant OilsAntifungal AgentsOils, VolatilePlant OilsAspergillus nigerCandida albicansCryptococcus neoformanscytotoxicityhuman breast tumor

Identifiers

PMID29954086
PMCPMC6100473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.