Evidence map›Paper›PMID 29953742›Full record

ArticleArthritis care & research2019

Relationship of Joint Hypermobility with Ankle and Foot Radiographic Osteoarthritis and Symptoms in a Community-Based Cohort.

Yvonne M Golightly, Marian T Hannan, Amanda E Nelson, Howard J Hillstrom, Rebecca J Cleveland, Virginia B Kraus, Todd A Schwartz, Adam P Goode, Portia Flowers, Jordan B Renner and 1 more

Abstract read
In one paragraph

Article in Arthritis care & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yvonne M GolightlyUniversity of North Carolina, Chapel Hill.ORCID 0000-0003-1205-2759
Marian T HannanInstitute for Aging Research, Hebrew Senior Life and Harvard Medical School, Boston, MA.ORCID 0000-0002-9586-6928
Amanda E NelsonUniversity of North Carolina, Chapel Hill.ORCID 0000-0002-9344-7877
Howard J HillstromHospital for Special Surgery, New York, New York.
Rebecca J ClevelandUniversity of North Carolina, Chapel Hill.
Virginia B KrausDuke University School of Medicine, Durham, North Carolina.ORCID 0000-0001-8173-8258
Todd A SchwartzUniversity of North Carolina, Chapel Hill.ORCID 0000-0002-0232-2543
Adam P GoodeDuke University School of Medicine, Durham, North Carolina.ORCID 0000-0002-0793-3298
Portia FlowersUniversity of North Carolina, Chapel Hill.
Jordan B RennerUniversity of North Carolina, Chapel Hill.
Joanne M JordanUniversity of North Carolina, Chapel Hill.
University of North Carolina at Chapel Hill · USDuke University · USHarvard University · USHospital for Special Surgery · US

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
NIAMS Multidisciplinary Clinical Research CenterP60AR064166 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHWARTZ, TODD A · 2013 to 2017
$5.8M
Foot Disorders, Pain and Physical Disability in EldersR01AR047853 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI HANNAN, MARIAN T. · 2002 to 2012
$5.1M
Johnston County Osteoarthritis Project: Arthritis, Disability, and Other Chronic DiseasesU01DP006266 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NELSON, AMANDA E · 2016 to 2020
$3.8M
The Johnston County OA Project: Arthritis and DisabilityU01DP003206 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2011 to 2015
$3.2M
Joint Hypermobility and Lower Body OsteoarthritisR01AR067743 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GOLIGHTLY, YVONNE M · 2015 to 2018
$1.6M
Variations in Hip Morphology: Frequency and Impact on Osteoarthritis OutcomesK23AR061406 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NELSON, AMANDA E · 2011 to 2015
$668k
ACL HHS U01DP003206CDC/Association of Schools of Public Health S043CDC/Association of Schools of Public Health S3486NCCDPHP CDC HHS U01 DP003206NCCDPHP CDC HHS U01 DP006266NIAMS NIH HHS K23 AR061406NIAMS NIH HHS P30 AR072580NIAMS NIH HHS P60 AR064166NIAMS NIH HHS R01 AR047853NIAMS NIH HHS R01 AR067743NIA NIH HHS P30 AG028716
6 · The paper itself

Abstract

objectiveTo explore associations of joint hypermobility (a condition where range of motion is greater than normal) with ankle and foot radiographic osteoarthritis (OA) and symptoms in a large community-based cohort of African American and white adults ages 55-94 years old.

methodsAnkle and foot radiographs and joint hypermobility data (Beighton score for joint hypermobility criteria) were available for 848 participants (from 2003 to 2010) in this cross-sectional study. General joint hypermobility was defined as a Beighton score ≥4 (range 0-9); knee hypermobility was defined as hyperextension of at least 1 knee. Standing anteroposterior and lateral foot radiographs were read with standard atlases for Kellgren-Lawrence grade, osteophytes, and joint space narrowing (JSN) at the tibiotalar joint, and for osteophytes and JSN to define OA at 5 foot joints. Ankle or foot symptoms were self-reported. Separate person-based logistic regression models were used to estimate associations of ankle and foot OA and symptom outcomes with hypermobility measures, adjusting for age, sex, race, body mass index, and history of ankle/foot injury.

resultsThis sample cohort included 577 women (68%) and 280 African Americans (33%). The mean age of the participants was 71 years, with a mean body mass index of 31 kg/m

conclusionKnee joint hypermobility may be related to talonavicular OA and to ankle and foot symptoms.

Indexed as

AgedAged, 80 and overAnkle JointCohort StudiesFemaleFoot JointsHumansJoint InstabilityKnee JointMaleMiddle AgedOsteoarthritis

Identifiers

PMID29953742
PMCPMC6310667
OpenAlexW2810087293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.