Evidence map›Paper›PMID 29953592›Full record

ArticleJournal of cellular physiology2018

Only a subpopulation of mouse sperm displays a rapid increase in intracellular calcium during capacitation.

Guillermina M Luque, Tomas Dalotto-Moreno, David Martín-Hidalgo, Carla Ritagliati, Lis C Puga Molina, Ana Romarowski, Paula A Balestrini, Liza J Schiavi-Ehrenhaus, Nicolas Gilio, Dario Krapf and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cellular physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

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  18. Starvation induces an increase in intracellular calcium and potentiates the progesterone-induced mouse sperm acrosome reaction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Guillermina M LuqueInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Tomas Dalotto-MorenoInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
David Martín-HidalgoDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA.
Carla RitagliatiInstituto de Biología Molecular y Celular de Rosario (IBR), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Rosario (UNR), Rosario, Argentina.
Lis C Puga MolinaInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Ana RomarowskiInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Paula A BalestriniInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Liza J Schiavi-EhrenhausInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Nicolas GilioInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Dario KrapfInstituto de Biología Molecular y Celular de Rosario (IBR), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Rosario (UNR), Rosario, Argentina.
Pablo E ViscontiDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA.
Mariano G BuffoneInstituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.ORCID 0000-0002-7163-6482
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Massachusetts Amherst · US

Funding

Sperm Ca2+ Signaling and Energy Pathways in basic science and ARTR01HD038082 · NICHD · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI VISCONTI, PABLO E. · 2000 to 2025
$6.5M
ROLE OF ACTIN CYTOSKELETON DURING MOUSE SPERM ACROSOMAL EXOCYTOSISR01TW008662 · FIC · FUND INST BIOL Y MED EXPERIMENTAL · PI BUFFONE, MARIANO G · 2012 to 2016
$262k
FIC NIH HHS R01 TW008662NICHD NIH HHS R01 HD038082
6 · The paper itself

Abstract

Mammalian sperm must undergo a functionally defined process called capacitation to be able to fertilize oocytes. They become capacitated in vivo by interacting with the female reproductive tract or in vitro in a defined capacitation medium that contains bovine serum albumin, calcium (Ca

Indexed as

AnimalsCalciumCalcium ChannelsCalcium SignalingFemaleFlow CytometryGene Knockout TechniquesGenitalia, FemaleHumansMaleMiceMice, KnockoutSpermatozoaSperm CapacitationSperm MotilityCalciumCalcium ChannelsCatsper1 protein, mousecalciumcapacitationCatSpersperm

Identifiers

PMID29953592
PMCPMC6185779
OpenAlexW2809745360

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.