SynthesisPloS one2018
Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- Adolescent condom use in Southern Africa: narrative systematic review and conceptual model of multilevel barriers and facilitators.BMC public health · 2021Pooled it
- Association of Sexual Health Interventions With Sexual Health Outcomes in Black Adolescents: A Systematic Review and Meta-analysis.JAMA pediatrics · 2020Pooled it
- A Randomized Controlled Trial of a Digital Intervention to Improve the Sexual Health of Adolescent and Young Adult Male Emergency Department Patients.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Trial
- Efficacy of mobile-based educational intervention using Instructional Systems Design in promoting preventive behaviors for sexually transmitted infections among Iranian women: a randomized controlled trial.BMC public health · 2024Trial
- High School FLASH Sexual Health Education Curriculum: LGBTQ Inclusivity Strategies Reduce Homophobia and Transphobia.Prevention science : the official journal of the Society for Prevention Research · 2023Trial
- Effects of a Sexual Risk-Reduction Intervention for Teenagers: A Cluster-Randomized Control Trial.AIDS and behavior · 2022Trial
- Engaging parents in digital sexual and reproductive health education: evidence from the JACK trial.Reproductive health · 2020Trial
- Article
- Awareness and predictors of knowledge about sexually transmitted diseases among early adolescents in koforidua, ghana: a mixed-methods study.Reproductive health · 2025Article
- Indigenous Mothers' Perspective on Sexual Health in Northwest Territories, Canada: Results from the Maternal and Infant Health Project.Journal of community health · 2025Article
- Effectiveness of a Comprehensive School-Based Sex Education Program for Young Adolescents in the Netherlands.Journal of youth and adolescence · 2024Article
- Prevalence of risky sexual behavior and associated factors among Injibara University students, Northwest Ethiopia.Frontiers in reproductive health · 2024Article
- Predicting Adolescent Intervention Non-responsiveness for Precision HIV Prevention Using Machine Learning.AIDS and behavior · 2023Article
- The role of structural factors for preventing HIV risk practices among adolescents in South Africa: A three-wave analysis of caregiving, education, food security, and social protection.Research square · 2023Article
- Adolescent: provider connectedness and STI risk reduction following a brief alcohol intervention: findings from a randomized controlled trial.Frontiers in psychology · 2023Article
- Pilot Implementation of a User-Driven, Web-Based Application Designed to Improve Sexual Health Knowledge and Communication Among Young Zambians: Mixed Methods Study.Journal of medical Internet research · 2022Article
- An Evidence Map on Serious Games in Preventing Sexually Transmitted Infections Among Adolescents: Systematic Review About Outcome Categories Investigated in Primary Studies.JMIR serious games · 2022Review
- Determinants of syphilis infection among pregnant women attending antenatal care in hospitals of Wolaita zone, Southern Ethiopia, 2020.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundNumerous studies have evaluated the efficacy of interventions to reduce risk for sexually transmitted infections in adolescents in recent years, but their global effects remain unknown since 2008, the last date of a comprehensive review of prior studies.
aimsThis study aims at evaluating the efficacy of interventions to promote sexual health, reduce STIs and unplanned pregnancies targeted to adolescents available after 2008; and analyzing the moderators of their global efficacy.
methodsWe searched electronic databases and manual searches of some journals focused on STIs in May 2016. The studies evaluated the efficacy of interventions to reduce sexual risk in adolescents (age range: 11-19) anywhere in the world. Effect size of the relevant outcomes for sexual risk was calculated for every study. Analyses incorporated random-effect assumptions for each outcome. The homogeneity in the results was examined with the I2 statistic and its associated 95% confident interval.
resultsData from 63 studies (59,795 participants) were analyzed for behavioral and non-behavioral outcomes. In the short term, interventions had a positive impact in sexual health-related knowledge (Hedges'g = 1.01), attitudes (g = 0.29), self-efficacy toward condom use (g = 0.22), intention to refuse sex (g = 0.56), condom use intention (g = 0.46), and condom use (g = 0.38). In the medium term, positive effects observed at the short-term were maintained, although effect size significantly decreased in all variables. In the long term, interventions improved condom use (g = 0.47). Moderators of the efficacy are discussed.
conclusionsSexual health promotion interventions are effective to promote sexual health through increasing condom use. Effects on non-behavioral variables tend to decrease over time, while condom use increased in the long-term. Interventions should focus on the long-term efficacy, especially in behavioral and biological measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.