Observational studyMedicine2018
Vitamin D status in South Korean population: Seven-year trend from the KNHANES.
Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Effects of intermittent or single high-dose vitamin D supplementation on risk of falls and fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Association of serum 25(OH)Vit-D levels with risk of pediatric fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Pooled it
- Upward changes in serum 25-hydroxyvitamin D levels in South Korea: the Korea National Health and Nutrition Examination Survey studies IX (2022-2023) versus VI (2013-2014).Osteoporosis and sarcopenia · 2026Article
- Review
- Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials.Endocrinology and metabolism (Seoul, Korea) · 2026Review
- Article
- Association between vitamin D status and insulin resistance in Korean adolescents: differential effects of obesity using non-insulin-based indices.BMC pediatrics · 2026Article
- Low Serum 25-Hydroxyvitamin D as a Risk Factor for Frailty in Community-Dwelling Older Men: A Korean Nationwide Study.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Ten-year trends in dietary vitamin D intake and its food sources among Koreans: based on the 2013-2022 Korea National Health and Nutrition Examination Survey data.Nutrition research and practice · 2025Article
- Non-Linear Associations Between Serum Vitamin D and Uric Acid in Korean Adults: 2022-2023 KNHANES Data.Nutrients · 2025Article
- Impact of Heavy Metals on the Antioxidant Activity of Vitamin D: A Metabolic Perspective.Metabolites · 2025Article
- Contemporary factors affecting serum 25-hydroxyvitamin D concentrations in Chinese children aged 2-6 years.Public health nutrition · 2025Article
- Serum 25(OH)D Levels and Risk of Nonalcoholic Fatty Liver Disease in Nonobese and Lean Individuals.Yonsei medical journal · 2025Article
- Article
- Association between serum vitamin D deficiency and visceral fat indices in adolescents: The Ewha Birth and growth cohort study.PloS one · 2025Article
- Vitamin D supplementation can improve the 28-day mortality rate in patients with sepsis-associated acute kidney injury.Renal failure · 2024Article
- Development and validation of a semi-quantitative food frequency questionnaire as a tool for assessing dietary vitamin D intake among Korean women.Nutrition research and practice · 2024Article
- Insulin Resistance and Impaired Insulin Secretion Predict Incident Diabetes: A Statistical Matching Application to the Two Korean Nationwide, Population-Representative Cohorts.Endocrinology and metabolism (Seoul, Korea) · 2024Article
- Association between Vitamin D Deficiency and Serologic Response to Hepatitis B Virus Vaccination among Heavy Industry Workers.Vaccines · 2024Article
- Determining the vitamin D supplementation duration to reach an adequate or optimal vitamin D status and its effect on blood lipid profiles: a longitudinal study.Journal of health, population, and nutrition · 2024Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D deficiency has become one of the most prevalent health problems in modern society. However, there has been no study that has reported the trend of vitamin D status in Asia. We performed an observational study to investigate the trend of vitamin D status in South Korea based on a representative national database acquired from the Korea National Health and Nutrition Examination Surveys (KNHANES) conducted from 2008 to 2014. A total of 39,759 patients were included in the final analyses. Serum 25-hydroxyvitamin D (25 (OH)D) levels were measured by radioimmunoassay. The overall mean serum level of 25 (OH)D was 45.7 nmol/L in males and 40.9 nmol/L in females in KNHANES 2008 to 2014. There was a significant trend toward lower serum 25 (OH)D levels from 2008 to 2014 in males by -1.2 (95% confidence interval [CI] -1.5 to -0.9) nmol/L per year and in female by -0.7 (95% CI -0.9 to -0.4) nmol/L per year. The overall mean serum level of 25 (OH)D in 2008 was 53.0 nmol/L in males and 45.7 nmol/L in females. It decreased to 43.2 nmol/L in males and 39.2 nmol/L in females in 2014. Vitamin D deficiency, defined as the serum 25 (OH)D level of <50 nmol/L, was found in 65.7% of males and 76.7% of females in overall population. A significant increasing trend of vitamin D deficiency was also observed. The prevalence of vitamin D deficiency in 2008 was 51.8% in males and 68.2% in females, but rose to 75.2% and 82.5%, respectively, in 2014. The present study demonstrated that vitamin D status in South Koreans is still deteriorating. More extensive and proactive measures are needed to improve vitamin D status in South Korea.
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