Evidence map›Paper›PMID 29952935›Full record

ArticlePsychosomatic medicine

Chronic Physiologic Effects of Stress Among Lesbian, Gay, and Bisexual Adults: Results From the National Health and Nutrition Examination Survey.

Vickie M Mays, Robert-Paul Juster, Timothy J Williamson, Teresa E Seeman, Susan D Cochran

Abstract read
In one paragraph

Article in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Allostatic Load, Multimorbidity, and Overall and Cancer-Specific Survival among Older Adults in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
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  11. Sexual orientation and daily stress and well-being.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
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  12. Article
  13. Sexual identity differences in ideal cardiovascular health among cisgender adults in the All of Us Research Program.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Vickie M MaysFrom the Departments of Psychology and Health Policy and Management (Mays), Fielding School of Public Health University of California, Los Angeles; University of Montreal, Department of Psychiatry and Addiction (Juster), Montreal; University of California, Los Angeles (Williamson); UCLA School of Medicine and Fielding School of Public Health (Seeman), University of California, Los Angeles; and Department of Epidemiology, Fielding School of Public Health and Department of Statistics (Cochran), University of California, Los Angeles.
Robert-Paul Juster
Timothy J Williamson
Teresa E Seeman
Susan D Cochran
Angeles University Foundation · PHUniversity of California, Los Angeles · USUniversité de Montréal · CA

Funding

PREVENTION RESEARCH TRAINING:URBAN CHILDREN'S MENT HLTHT32MH015750 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHRISTINE DUNKEL SCHETTER · 1985 to 2026
$6.2M
Research Training/Education CoreP60MD006923 · NIMHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHOPTAW, STEVEN J · 2012 to 2016
$6.1M
Drug Use, HIV, and Other Comorbidities In A Vulnerable PopulationR01DA020826 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COCHRAN, SUSAN D · 2006 to 2010
$2.2M
Characteristics of suicide and homicide in a vulnerable populationR21MH115344 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COCHRAN, SUSAN D, MAYS, VICKIE M · 2018 to 2019
$410k
NIDA NIH HHS R01 DA020826NIMHD NIH HHS P60 MD006923NIMH NIH HHS R21 MH115344NIMH NIH HHS T32 MH015750
6 · The paper itself

Abstract

objectiveSocial disadvantage is associated with markers of physiological dysregulation, which is linked to disease trajectories. Chronic experiences with discrimination are thought to result in the accumulation of physiological "wear and tear" known as allostatic load (AL) among socially marginalized populations such as sexual minorities. Using a nationally representative US sample, we examined whether (1) people who self-identified as homosexual or bisexual display higher levels of AL than heterosexual individuals and (2) subgroups of sexual identity would further differ from each other as a consequence of distinct experiences of marginalization.

methodsWe use data from the 2001-2010 National Health and Nutrition Examination Survey. Employing multivariate regression methods with sex-specific analyses, we examined AL score differences among lesbian/gay (n = 211), bisexual (n = 307), homosexually experienced (n = 424), and exclusively heterosexual (n = 12,969) individuals, adjusting for possible confounding due to demographics, health indicators, and, among men, HIV infection status.

resultsResults indicate that elevated AL was more common in bisexual men compared with exclusively heterosexual men (adjusted β = 0.25, 95% confidence interval [CI] = 0.05 to 0.44), with significantly higher levels of glycosylated hemoglobin A1c (adjusted odd ratio = 3.51, 95% CI = 1.46-7.92) and systolic blood pressure (adjusted odd ratio = 2.07, 95% CI = 1.02 to 4.18). Gay-identified men evidenced significantly lower AL (adjusted β = -0.22, 95% CI = -0.41 to -0.04). No significant differences in AL were observed among women.

conclusionsThese findings indicate that physiological dysregulation is more common in bisexual males compared with all other men. The results are discussed with regard to differences in health outcomes between individuals with different sexual orientations.

Indexed as

Homosexuality, FemaleHomosexuality, MaleSexual and Gender MinoritiesAdultAllostasisBisexualityFemaleHealth SurveysHeterosexualityHumansMaleMiddle AgedStress, PsychologicalYoung Adult

Identifiers

PMID29952935
PMCPMC6214815
OpenAlexW2811325581

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.