ArticleBehavioral neuroscience2018
Effects of light at night on laboratory animals and research outcomes.
Article in Behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 63 citations in OpenAlex.
- Building bridges: Involvement of animal care staff and laboratory technicians in experimental planning and conduct of animal studies for better job satisfaction and science.Laboratory animals · 2026Article
- Article
- The Effects of Light on Vertebrate Welfare: A Review.Animals : an open access journal from MDPI · 2025Review
- Correspondence between sleep patterns and anhedonia in adult male mice exposed to early-life stress.Translational psychiatry · 2025Article
- Effects of the Probiotics Lactobacillus rhamnosus DM163 and Lactobacillus delbrueckii DPUL-F36 on Anxiety-Related and Emotional Behaviors in Male Wistar Rats Under an Altered Light-Dark Cycle.Brain and behavior · 2025Article
- Article
- Red Light Sensitivity of Non-image and Image Forming Visual Systems of Laboratory Rodents: Circadian Disruption and Behavioral Detection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Far-red LED light alters circadian rhythms and elicits dark-adapted ERG responses in rodents.PloS one · 2025Article
- The effects of music and darkness on radionuclide distribution during mice FDG-PET scan.Iranian journal of veterinary research · 2025Article
- Beyond Lux: methods for species and photoreceptor-specific quantification of ambient light for mammals.BMC biology · 2024Article
- The inhalation effect ofFood chemistry: X · 2024Article
- The cognitive impact of light: illuminating ipRGC circuit mechanisms.Nature reviews. Neuroscience · 2024Review
- Influence of white-light-emitting diodes on primary visual cortex layer 5 pyramidal neurons (V1L5PNs) and remodeling by blue-light-blocking lenses.International ophthalmology · 2024Article
- Circadian Rhythms Disrupted by Light at Night and Mistimed Food Intake Alter Hormonal Rhythms and Metabolism.International journal of molecular sciences · 2023Review
- The 5XFAD mouse model of Alzheimer's disease displays age-dependent deficits in habituation to a novel environment.Aging brain · 2023Article
- Vivarium Lighting as an Important Extrinsic Factor Influencing Animal-based Research.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023Review
- Mouse models of nonalcoholic steatohepatitis and their application to new drug development.Archives of pharmacal research · 2022Review
- Blue-Light-Blocking Lenses Ameliorate Structural Alterations in the Rodent Hippocampus.International journal of environmental research and public health · 2022Article
- Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies.Experimental neurology · 2022Review
- Effects of light pollution on photoperiod-driven seasonality.Hormones and behavior · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Light has substantial influences on the physiology and behavior of most laboratory animals. As such, lighting conditions within animal rooms are potentially significant and often underappreciated variables within experiments. Disruption of the light/dark cycle, primarily by exposing animals to light at night (LAN), disturbs biological rhythms and has widespread physiological consequences because of mechanisms such as melatonin suppression, sympathetic stimulation, and altered circadian clock gene expression. Thus, attention to the lighting environment of laboratory animals and maintaining consistency of a light/dark cycle is imperative for study reproducibility. Light intensity, as well as wavelength, photoperiod, and timing, are all important variables. Although modern rodent facilities are designed to facilitate appropriate light cycling, there are simple ways to modify rooms to prevent extraneous light exposure during the dark period. Attention to lighting conditions of laboratory animals by both researchers and research care staff ensures best practices for maintaining animal welfare, as well as reproducibility of research results. (PsycINFO Database Record
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.