Evidence map›Paper›PMID 29952388›Full record

ArticleSoft matter2018

Microrheology of DNA hydrogel gelling and melting on cooling.

Javier Fernandez-Castanon, Silvio Bianchi, Filippo Saglimbeni, Roberto Di Leonardo, Francesco Sciortino

Abstract read
In one paragraph

Article in Soft matter, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  11. Microrheology for biomaterial design.APL bioengineering · 2020
    Review
  12. Rational design of hydrogels to enhance osteogenic potential.Chemistry of materials : a publication of the American Chemical Society · 2020
    Article
  13. Article
  14. Gelling without Structuring: A SAXS Study of the Interactions among DNA Nanostars.Langmuir : the ACS journal of surfaces and colloids · 2020
    Article
  15. Article
  16. Increasing valence pushes DNA nanostar networks to the isostatic point.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Javier Fernandez-CastanonDipartimento di Fisica, "Sapienza" Università di Roma, Rome, I-00185, Italy. javier.fernandez.castanon@roma1.infn.it.ORCID http://orcid.org/0000-0002-9994-8461
Silvio BianchiCNR-NANOTEC, Soft and Living Matter Laboratory, Rome, I-00185, Italy.
Filippo SaglimbeniCNR-NANOTEC, Soft and Living Matter Laboratory, Rome, I-00185, Italy.
Roberto Di LeonardoDipartimento di Fisica, "Sapienza" Università di Roma, Rome, I-00185, Italy. javier.fernandez.castanon@roma1.infn.it and CNR-NANOTEC, Soft and Living Matter Laboratory, Rome, I-00185, Italy.
Francesco SciortinoDipartimento di Fisica, "Sapienza" Università di Roma, Rome, I-00185, Italy. javier.fernandez.castanon@roma1.infn.it and CNR-ISC, UOS "Sapienza" Università di Roma, Rome, I-00186, Italy.

Funding

European Research Council 307940
6 · The paper itself

Abstract

We present systematic characterisation by means of dynamic light scattering and particle tracking techniques of the viscosity and of the linear viscoelastic moduli, G'(ω) and G''(ω), for two different DNA hydrogels. These thermoreversible systems are composed of tetravalent DNA-made nanostars whose sticky sequence is designed to provide controlled interparticle bonding. While the first system forms a gel on cooling, the second one has been programmed to behave as a re-entrant gel, turning again to a fluid solution at low temperature. The frequency-dependent viscous and storage moduli and the viscosity reveal the different viscoelastic behavior of the two DNA hydrogels. Our results show how little variations in the design of the DNA sequences allow tuning of the mechanical response of these biocompatible all-DNA materials.

Indexed as

DNAHydrogelsTemperatureViscosityDNAHydrogels

Identifiers

PMID29952388
PMCPMC6295875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.