ReviewAnatolian journal of cardiology2018
Anemia in heart failure - from guidelines to controversies and challenges.
Review in Anatolian journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Impact of anemia on clinical outcomes in patients with acute heart failure: A systematic review and meta-analysis.Clinical cardiology · 2024Pooled it
- Hemoglobinometry at the point of care with activation of a hospital transfusion pathway versus usual care for the early detection of anaemia in primary care: the ANHEMOG randomized controlled trial.BMC primary care · 2026Trial
- Purine Metabolism Alterations in Patients with Chronic Heart Failure: A Cross-Sectional Study of Associations with Iron Status, Oxidative Stress, and Anemia.Metabolites · 2026Article
- Anemia in heart failure: evidence from a three-year cross-sectional study in Sudan.Journal of pharmaceutical health care and sciences · 2025Article
- Prevalence of anemia and its association with poor outcomes in acute heart failure patients in northeastern Thailand.International journal of emergency medicine · 2025Article
- Review
- Iron Deficiency in Heart Failure: From ESC Guidelines to Clinical Practice at a Romanian Hospital.Biomedicines · 2025Article
- Development and validation of an interpretable machine learning model for predicting the risk of non-cardiac surgery postoperative heart failure: a multicenter study.Frontiers in medicine · 2025Article
- White blood cell-to-haemoglobin ratio as a predictor of 30-day mortality in ICU patients with pulmonary hypertension: a MIMIC-IV database study.BMC cardiovascular disorders · 2024Observational
- The Effect of Direct Anticoagulant Therapy on Haematological Parameters in Atrial Fibrillation: Clinical Significance of Subclinical Haemoglobin Decrease.Medicina (Kaunas, Lithuania) · 2024Article
- Review
- The effect of the four pharmacological pillars of heart failure on haemoglobin level.Annals of medicine and surgery (2012) · 2024Review
- Association between white blood cell-to-haemoglobin ratio and 30 day mortality in heart failure in intensive care unit.ESC heart failure · 2024Article
- Right ventricular function and anemia in heart failure with preserved ejection fraction.Frontiers in cardiovascular medicine · 2024Article
- Why Is Iron Deficiency/Anemia Linked to Alzheimer's Disease and Its Comorbidities, and How Is It Prevented?Biomedicines · 2023Review
- Hepatic Venous Stasis Index Reflects Hepatic Congestion and Predicts Adverse Outcomes in Patients With Heart Failure.Journal of the American Heart Association · 2023Article
- Anaemia and Congestion in Heart Failure: Correlations and Prognostic Role.Biomedicines · 2023Article
- Acute Heart Failure: Diagnostic-Therapeutic Pathways and Preventive Strategies-A Real-World Clinician's Guide.Journal of clinical medicine · 2023Review
- Effects of Endothelin-1 and nitric oxide levels on myocardial ischemia-reperfusion injury.Annals of translational medicine · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anemia associated with heart failure is a frequent condition, which may lead to heart function deterioration by the activation of neuro-hormonal mechanisms. Therefore, a vicious circle is present in the relationship of heart failure and anemia. The consequence is reflected upon the patients' survival, quality of life, and hospital readmissions. Anemia and iron deficiency should be correctly diagnosed and treated in patients with heart failure. The etiology is multifactorial but certainly not fully understood. There is data suggesting that the following factors can cause anemia alone or in combination: iron deficiency, inflammation, erythropoietin levels, prescribed medication, hemodilution, and medullar dysfunction. There is data suggesting the association among iron deficiency, inflammation, erythropoietin levels, prescribed medication, hemodilution, and medullar dysfunction. The main pathophysiologic mechanisms, with the strongest evidence-based medicine data, are iron deficiency and inflammation. In clinical practice, the etiology of anemia needs thorough evaluation for determining the best possible therapeutic course. In this context, we must correctly treat the patients' diseases; according with the current guidelines we have now only one intravenous iron drug. This paper is focused on data about anemia in heart failure, from prevalence to optimal treatment, controversies, and challenges.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.