Evidence map›Paper›PMID 29951855›Full record

ArticleJournal of mathematical biology2018

Reconstructing gene trees from Fitch's xenology relation.

Manuela Geiß, John Anders, Peter F Stadler, Nicolas Wieseke, Marc Hellmuth

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Article in Journal of mathematical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Predicting horizontal gene transfers with perfect transfer networks.Algorithms for molecular biology : AMB · 2024
    Article
  2. The Theory of Gene Family Histories.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  3. Relative timing information and orthology in evolutionary scenarios.Algorithms for molecular biology : AMB · 2023
    Article
  4. Article
  5. Indirect identification of horizontal gene transfer.Journal of mathematical biology · 2021
    Article
  6. Article
  7. Reciprocal best match graphs.Journal of mathematical biology · 2020
    Article
  8. Reconstruction of time-consistent species trees.Algorithms for molecular biology : AMB · 2020
    Article
  9. Article
  10. Best match graphs.Journal of mathematical biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manuela GeißBioinformatics Group, Department of Computer Science, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
John AndersBioinformatics Group, Department of Computer Science, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Peter F StadlerBioinformatics Group, Department of Computer Science, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Nicolas WiesekeSwarm Intelligence and Complex Systems Group, Department of Computer Science, Leipzig University, Augustusplatz 10, 04109, Leipzig, Germany.
Marc HellmuthInstitute of Mathematics and Computer Science, University of Greifswald, Walther-Rathenau-Straße 47, 17487, Greifswald, Germany. mhellmuth@mailbox.org.

Funding

Bundesministerium für Bildung und Forschung 031A538ADeutscher Akademischer Austauschdienst 278966
6 · The paper itself

Abstract

Two genes are xenologs in the sense of Fitch if they are separated by at least one horizontal gene transfer event. Horizonal gene transfer is asymmetric in the sense that the transferred copy is distinguished from the one that remains within the ancestral lineage. Hence xenology is more precisely thought of as a non-symmetric relation: y is xenologous to x if y has been horizontally transferred at least once since it diverged from the least common ancestor of x and y. We show that xenology relations are characterized by a small set of forbidden induced subgraphs on three vertices. Furthermore, each xenology relation can be derived from a unique least-resolved edge-labeled phylogenetic tree. We provide a linear-time algorithm for the recognition of xenology relations and for the construction of its least-resolved edge-labeled phylogenetic tree. The fact that being a xenology relation is a heritable graph property, finally has far-reaching consequences on approximation problems associated with xenology relations.

Indexed as

Gene Transfer, HorizontalModels, GeneticMultigene FamilyPhylogenyAlgorithmsComputer SimulationGene DuplicationGenetic SpeciationHeuristicsMathematical ConceptsDi-cographFitch xenologyFixed parameter tractableForbidden induced subgraphsHeritable graph propertyInformative triple setsLeast-resolved treePhylogenetic treeRecognition algorithmRooted triples

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.