Trial reportEuropean archives of psychiatry and clinical neuroscience2019
Effects of physical activity on cognitive performance: a controlled clinical study in depressive patients.
Trial report in European archives of psychiatry and clinical neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Efficacy of different exercise interventions on cognitive function in adults with major depressive disorder and subthreshold depression: a systematic review with pairwise and network meta-analyses.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- Predicting Response to Pro-Cognitive Interventions in Mood Disorders: A Systematic Review by the International Society for Bipolar Disorders Targeting Cognition Task Force.Acta psychiatrica Scandinavica · 2026Pooled it
- Effects of exercise on cognitive function in patients with depression: a three-level meta-analysis with dose-response and exploratory mediation analyses.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- Pooled it
- Optimal dose and type of exercise to improve cognitive function in adults with major depressive disorder: a systematic review and Bayesian model-based network meta-analysis.Frontiers in public health · 2025Pooled it
- Intervention effect of exercise on working memory in patients with depression: a systematic review.PeerJ · 2024Pooled it
- Effects of Exercise Training on Executive Functioning in Adults with Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Effects of Physical Exercise on Executive Function in Adults with Depression: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- The impact of aerobic endurance training on cognitive performance in schizophrenic inpatients in a clinical routine setting.European archives of psychiatry and clinical neuroscience · 2025Trial
- Move to Remember: The Role of Physical Activity and Exercise in Preserving and Enhancing Cognitive Function in Aging-A Narrative Review.Geriatrics (Basel, Switzerland) · 2025Review
- Digital measures of activity and motivation impact depression and anxiety in the real world.NPJ digital medicine · 2025Article
- The mediating role of life satisfaction in the relationship between physical exercise and depressive symptoms among middle-aged and elderly individuals.Frontiers in public health · 2025Article
- A systematic review of occupation- and activity-based health management interventions for adult patients with severe mental disorders.Journal of education and health promotion · 2025Article
- The intervention effect of exercise on the attention of patients with depression: a systematic review.Frontiers in psychology · 2025Review
- The effects of aerobic exercise on cognitive function and depressive symptom in patients with depression: a systematic review and meta-analysis of randomized controlled trials.American journal of translational research · 2025Review
- Outcomes of the effect of exercise on cognitive function in patients with depression: A meta-analysis.World journal of psychiatry · 2024Article
- Relationships between depression, anxiety, and motivation in the real-world: Effects of physical activity and screentime.medRxiv : the preprint server for health sciences · 2024Article
- From movement to motivation: a proposed framework to understand the antidepressant effect of exercise.Translational psychiatry · 2024Review
- Article
- Effectiveness of Group Physical Exercise in Treating Major Depressive Disorder: An Analysis of Secondary Data from an Aborted Randomized Trial.Behavioral sciences (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical activity is a common adjunctive therapy in psychiatric and psychosomatic hospitals. In the present study, we assessed the effects of an exercise program, integrated into routine inpatient treatment, on cognitive performance and subjective severity of depression in a sample of patients suffering from major depression. We randomized n = 38 patients with unipolar depression to either physical exercise (n = 18) or occupational therapy as an active control treatment (n = 20). Both treatments were delivered in group format over a period of 3-4 weeks. Data indicate that there were significant improvements of cognitive functions and depressive symptoms in both groups, with specific treatment effects in reaction time and in short-term verbal memory favoring the physical activity group. In conclusion, we found physical exercise to be a feasible, easy-to-implement add-on therapy for depressive patients with promising effects on cognitive performance. However, these results need to be replicated in larger samples with an extended follow-up.
Indexed as
Identifiers
29951850What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.