Evidence map›Paper›PMID 29951724›Full record

ArticleClinical and experimental nephrology2019

Relationship between abdominal adiposity and incident chronic kidney disease in young- to middle-aged working men: a retrospective cohort study.

Akihiro Kuma, Bungo Uchino, Yoko Ochiai, Masatoshi Kawashima, Kazuhiko Enta, Masahito Tamura, Yutaka Otsuji, Akihiko Kato

Abstract read
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In one paragraph

Article in Clinical and experimental nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Akihiro KumaSecond Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan. akihiro_k@me.com.
Bungo UchinoHealth Promotion Center, Yamaha Motor Co., Ltd., 2500 Shingai, Iwata, 438-8501, Japan.
Yoko OchiaiHealth Promotion Center, Yamaha Motor Co., Ltd., 2500 Shingai, Iwata, 438-8501, Japan.
Masatoshi KawashimaHealth Care Center, Central Japan Railway Company, 1-21-19 Meieki-Minami, Nakamura-ku, Nagoya, 450-0003, Japan.
Kazuhiko EntaHealth Care Center, Central Japan Railway Company, 1-21-19 Meieki-Minami, Nakamura-ku, Nagoya, 450-0003, Japan.
Masahito TamuraKidney Center, University Hospital of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan.
Yutaka OtsujiSecond Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Akihiko KatoBlood Purification Unit, Hamamatsu University Hospital, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3125, Japan.
University of Occupational and Environmental Health Japan · JPCentral Japan Railway (Japan) · JPYamaha (Japan) · JPHamamatsu University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a risk factor for the development of chronic kidney disease (CKD). However, it remains to be fully examined whether fatness is more useful in predicting incident CKD. We aimed this study to determine the association of body fat, body mass index and waist circumference (WC) with subsequent changes in estimated glomerular filtration rate (eGFR) and incident CKD in young- to middle-aged working men.

methodsWe analyzed data from annual health check-up in male workers aged from 20 to 60 years with basal eGFR of 60-90 mL/min/1.73 m

resultsThere were 8,015 men participants. During the 5-year follow-up, 11.0% of the participants (N = 878) had developed to incident CKD. When basal WC was greater than 80.0 cm, which was decided by Youden's Index, there was a significantly higher risk of incident CKD [OR 1.57 (95% confident interval 1.35-1.84)]. Changes in WC over 5 years were significantly related to eGFR decline in young men (< 40 years old) with normal blood pressures and normoglycemia.

conclusionsThese findings suggest that WC > 80.0 cm is a risk factor for incident CKD and strongly associated with a decline in eGFR in the young- to middle-aged working healthy men.

Indexed as

AdiposityAdultAgingBody Mass IndexCohort StudiesDiabetes MellitusFollow-Up StudiesGlomerular Filtration RateHumansHypertensionJapanMaleMiddle AgedObesity, AbdominalReference ValuesRenal Insufficiency, ChronicBody mass indexChronic kidney diseaseTotal body fatnessWaist circumferenceWorking men

Identifiers

PMID29951724
OpenAlexW2810114195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.