Evidence map›Paper›PMID 29951642›Full record

ArticleEuropean journal of hybrid imaging2018

Myocardial blood flow and myocardial flow reserve values in

Opstal Tsj, Knol Rjj, Cornel Jh, Wondergem M, van der Zant Fm

Open access · goldAbstract read
In one paragraph

Article in European journal of hybrid imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  14. Normal values of thermodilution-derived absolute coronary blood flow and microvascular resistance in humans.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021
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  16. Ventricular synchrony is not significantly determined by absolute myocardial perfusion in patients with chronic heart failure: AJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Opstal TsjDepartment of Nuclear Medicine, North West Clinics, Alkmaar, The Netherlands.
Knol RjjDepartment of Nuclear Medicine, North West Clinics, Alkmaar, The Netherlands.
Cornel JhCardiac Imaging Division Alkmaar, North West Clinics, Alkmaar, The Netherlands.
Wondergem MDepartment of Nuclear Medicine, North West Clinics, Alkmaar, The Netherlands.
van der Zant FmDepartment of Nuclear Medicine, North West Clinics, Alkmaar, The Netherlands.
Medisch Centrum Alkmaar · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac imaging by means of myocardial Positron Emission Tomography/Computed Tomography (PET/CT) is being used increasingly to assess coronary artery disease, to guide revascularization decisions with more accuracy, and it allows robust quantitative analysis of both regional myocardial blood flow (MBF) and myocardial flow reserve (MFR).Recently, a more time-efficient protocol has been developed in combination with a residual activity correction algorithm in which a stress acquisition is performed directly after completion of the rest acquisition to subtract remaining myocardial radioactivity.The objective of this study is to define flow values of myocardial blood flow (MBF) and Myocardial Flow Reserve (MFR) with

resultsA mean MBF in rest of 1.02 ± 0.22 ml/g/min, a mean MBF in stress of 2.54 ± 0.41 ml/g/min with a mean MFR of 2.60 ± 0.61 were measured. Female patients had a significant higher MBF in rest and stress, but lower MFR; a small but significant negative correlation was measured between age and MBF in stress and MFR. Residual activity correction had a significant effect resulting in a difference in global stress MBF before and after correction of 0.39 ± 0.13 ml/g/min.

conclusionsThis study established flow values for

Indexed as

13 N–ammoniaFlow reserveMyocardial PET/CTResidual activity correctionStress flowTime-efficient protocol

Identifiers

PMID29951642
PMCPMC5994394
OpenAlexW2805348764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.