Evidence map›Paper›PMID 29951557›Full record

ArticleJournal of immunology research2018

Integrin

Yan-Li Zhang, Xin Xing, Li-Bo Cai, Lei Zhu, Xiao-Mei Yang, Ya-Hui Wang, Qin Yang, Hui-Zhen Nie, Zhi-Gang Zhang, Jun Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
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  4. α9β1 integrin & its ligands as new potential biomarkers in FMF.The Indian journal of medical research · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. RHO GTPase family in hepatocellular carcinoma.Experimental hematology & oncology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yan-Li ZhangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
Xin XingDepartment of Obstetrics and Gynecology, Fengxian Hospital, Shanghai 201499, China.ORCID 0000-0002-4766-4926
Li-Bo CaiDepartment of Accident and Emergency, Heihe No. 1 People's Hospital, Heihe 164300, China.
Lei ZhuState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
Xiao-Mei YangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
Ya-Hui WangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
Qin YangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
Hui-Zhen NieState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
Zhi-Gang ZhangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.ORCID 0000-0001-8965-223X
Jun LiState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.ORCID 0000-0003-0423-3381
Xue-Li ZhangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.ORCID 0000-0001-8306-0639
Shanghai Jiao Tong University · CNHeihe University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrin subunit alpha 9 (ITGA9) mediates cell-cell and cell-matrix adhesion, cell migration, and invasion through binding different kinds of extracellular matrix (ECM) components. However, its potential role and underlying molecular mechanisms remain unclear in hepatocellular carcinoma (HCC). Here, we found that ITGA9 expression was obviously decreased in patients with HCC, which was negatively correlated with HCC growth and metastasis. ITGA9 overexpression significantly inhibited cell proliferation and migration

Indexed as

Signal TransductionAdultAgedAnimalsBiomarkersCarcinoma, HepatocellularCell Line, TumorCell MovementCell ProliferationDisease Models, AnimalFemaleFocal Adhesion Protein-Tyrosine KinasesGene ExpressionGene Expression ProfilingHeterograftsHumansBiomarkersFocal Adhesion Protein-Tyrosine Kinasesintegrin alpha9Integrin alpha Chainsrho GTP-Binding Proteins

Identifiers

PMID29951557
PMCPMC5989280
OpenAlexW2804158650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.