Evidence map›Paper›PMID 29951552›Full record

Trial reportJournal of diabetes research2018

Characterization of the Cicatrization Process in Diabetic Foot Ulcers Based on the Production of Reactive Oxygen Species.

Alberto López-Delis, Suélia de S Rodrigues Fleury Rosa, Paulo Eduardo Narcizo de Souza, Marcella Lemos Brettas Carneiro, Mário Fabrício Fleury Rosa, Yasmin Carneiro Lobo Macedo, Fabiane Hiratsuka Veiga-Souza, Adson Ferreira da Rocha

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Alberto López-DelisMedical Biophysics Center, University of Oriente, Santiago de Cuba, Cuba.ORCID 0000-0002-0826-5914
Suélia de S Rodrigues Fleury RosaBiomedical Engineering Program, University of Brasilia, Brasilia, DF, Brazil.ORCID 0000-0002-1247-9050
Paulo Eduardo Narcizo de SouzaLaboratory of Electron Paramagnetic Resonance, Institute of Physics, University of Brasilia, Brasilia, DF, Brazil.ORCID 0000-0002-4289-8678
Marcella Lemos Brettas CarneiroFaculty of Planaltina, University of Brasilia, Planaltina, GO, Brazil.ORCID 0000-0002-6165-0969
Mário Fabrício Fleury RosaBiomedical Engineering Program, University of Brasilia, Brasilia, DF, Brazil.ORCID 0000-0002-4821-9007
Yasmin Carneiro Lobo MacedoBiomedical Engineering Program, University of Brasilia, Brasilia, DF, Brazil.ORCID 0000-0003-2778-4100
Fabiane Hiratsuka Veiga-SouzaLaboratory of Biochemistry and Protein Chemistry, Institute of Biological Sciences, University of Brasilia, Brasilia, DF, Brazil.ORCID 0000-0002-5300-5038
Adson Ferreira da RochaBiomedical Engineering Program, University of Brasilia, Brasilia, DF, Brazil.ORCID 0000-0003-4532-1791
Universidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aims at evaluating the correlation between the free radical formation and the healing action of lower limbs' ulcers in a randomized controlled trial with the use of an adhesive derived from natural latex associated with a light-emitting diode (LED) circuit. The sample consists of 15 participants with lower limb lesions divided into three groups: group 1 case (5 participants) received the proposed dressing system adhesive of the natural latex associated with the LED circuit; group 2 control (5 participants) received the dressings at home performed by nurses according to and established by the clinic of wounds (treated with calcium alginate or silver foam); and group 3 (5 participants) also received the dressing in their homes with the use of the dressing adhesive derived from the natural latex associated with the LED circuit. The collected data were analyzed qualitatively and quantitatively by electron paramagnetic resonance for determination of free radical formation. Kruskal-Wallis statistical test was used to evaluate the effect of treatment on the lower limb's ulcer cicatrization process and its correlation with free radical. The results obtained corroborated the hypothesis about the reduction of the quantity of these molecules in the end of treatment related to the healing wound.

Indexed as

BandagesAgedAlginatesCicatrixDiabetic FootFemaleGlucuronic AcidHexuronic AcidsHumansMaleMiddle AgedReactive Oxygen SpeciesTreatment OutcomeWound HealingAlginatesGlucuronic AcidHexuronic AcidsReactive Oxygen Species

Identifiers

PMID29951552
PMCPMC5989169
OpenAlexW2804719137

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.