Evidence map›Paper›PMID 29951524›Full record

SynthesisBioMed research international2017

Safety and Efficacy of First-Line Treatments for Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Indirect Comparison.

Haofeng Zheng, Jialiang Chen, Wenhan Qiu, Sijie Lin, Yanxiong Chen, Guancan Liang, Youqiang Fang

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. [Cancers · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Physical properties and pharmacological applications of CoWorld journal of microbiology & biotechnology · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Haofeng ZhengDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
Jialiang ChenDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
Wenhan QiuDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
Sijie LinDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
Yanxiong ChenDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
Guancan LiangDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
Youqiang FangDepartment of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.ORCID 0000-0001-7814-4889
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, several drugs have been introduced for the first-line treatment of chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC), but few studies have compared treatment outcomes directly. This indirect comparison among 10 clinical trials (

Indexed as

Antineoplastic AgentsDisease-Free SurvivalDocetaxelHumansMaleProstate-Specific AntigenProstatic Neoplasms, Castration-ResistantQuality of LifeTaxoidsTreatment OutcomeAntineoplastic AgentsDocetaxelProstate-Specific AntigenTaxoids

Identifiers

PMID29951524
PMCPMC5989298
OpenAlexW2773024035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.