Evidence map›Paper›PMID 29951493›Full record

ArticleAnnals of translational medicine2018

The impact of

Xiao-Xiao Chen, Run-Rong Guo, Xi-Peng Cao, Lin Tan, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative

Open access · hybridAbstract read
In one paragraph

Article in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiao-Xiao ChenDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.
Run-Rong GuoDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.
Xi-Peng CaoClinical Research Center, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.
Lin TanDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.
Lan TanDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266071, China.
Alzheimer’s Disease Neuroimaging Initiative
Qingdao University · CN

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

backgroundGrowth factor receptor-bound protein-associated binding protein 2 gene (

methodsWe evaluated the connection between four single nucleotide polymorphisms (SNPs) of

resultsrs1385600 and rs1007837 were significantly associated with all the three biomarkers in CSF (rs1385600: Aβ Pc =0.0112, T-tau Pc =0.0356, P-tau Pc =0.0116; rs1007837: Aβ Pc =0.0058, T-tau Pc =0.0278, P-tau Pc =0.0231). rs2373115 only showed significant association with Aβ and P-tau (Aβ, Pc=0.0398, P-tau, Pc=0.0329). rs10793294 showed no significant association with all the three biomarkers.

conclusionsOur study suggested that

Indexed as

Alzheimer’s disease (AD)Alzheimer’s Disease Neuroimaging Initiative (ADNI)cerebrospinal fluid (CSF) biomarkersGAB2single nucleotide polymorphisms (SNPs)

Identifiers

PMID29951493
PMCPMC5994512
OpenAlexW2804336510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.