ArticleJournal of biomedical physics & engineering2018
Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects.
Article in Journal of biomedical physics & engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 49 citations in OpenAlex.
- Thalamic Neuromodulation: New Frontiers.Epilepsy currents · 2026Article
- From deep brain stimulation to brain-computer interfaces: current progress in implantable neurotechnology.Frontiers in neuroscience · 2026Review
- Technological Advances and Medical Applications of Implantable Electronic Devices: From the Heart, Brain, and Skin to Gastrointestinal Organs.Biosensors · 2025Review
- Neurophysiological Markers of Reward Processing Can Inform Preclinical Neurorehabilitation Approaches for Cognitive Impairments Following Brain Injury.Brain sciences · 2025Review
- Big data for neuroscience in the context of predictive, preventive, and personalized medicine.The EPMA journal · 2025Review
- Adaptive fuzzy iterative learning control based neurostimulation system and in-silico evaluation.Cognitive neurodynamics · 2024Article
- Closed-loop recruitment of striatal interneurons prevents compulsive-like grooming behaviors.Nature neuroscience · 2024Article
- Landscape and future directions of machine learning applications in closed-loop brain stimulation.NPJ digital medicine · 2023Review
- Suppression of seizure in childhood absence epilepsy using robust control of deep brain stimulation: a simulation study.Scientific reports · 2023Article
- Monitoring time domain characteristics of Parkinson's disease using 3D memristive neuromorphic system.Frontiers in computational neuroscience · 2023Article
- Review
- Electrical brain stimulation and continuous behavioral state tracking in ambulatory humans.Journal of neural engineering · 2022Article
- Identification of effective features of LFP signal for making closed-loop deep brain stimulation in parkinsonian rats.Medical & biological engineering & computing · 2022Article
- Polymer Ring Resonator with a Partially Tapered Waveguide for Biomedical Sensing: Computational Study.Sensors (Basel, Switzerland) · 2021Article
- Oxidative stress factors in Parkinson's disease.Neural regeneration research · 2021Review
- OPETH: Open Source Solution for Real-Time Peri-Event Time Histogram Based on Open Ephys.Frontiers in neuroinformatics · 2020Article
- Intracortical Dynamics Underlying Repetitive Stimulation Predicts Changes in Network Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Circuit Investigations With Open-Source Miniaturized Microscopes: Past, Present and Future.Frontiers in cellular neuroscience · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deep brain stimulation (DBS) is known as the most effective technique in the treatment of neurodegenerative diseases, especially Parkinson disease (PD) and epilepsy. Relative healing and effective control of disease symptoms are the most significant reasons for the tangible tendency in use and development of this technology. Nevertheless, more cellular and molecular investigations are required to reveal the detailed mechanism of DBS. Here, we reviewed the methods, challenges and the ways to overcome the limitations of DBS. Also, challenges in probe fabrication technology, material selection, related mechanical stability and biocompatibility concerns are discussed. Finally, closed- and open-loop stimulation systems were compared.
Indexed as
Identifiers
29951448PMC6015649W2806145184What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.