Evidence map›Paper›PMID 29951376›Full record

ArticleFrontiers in cellular and infection microbiology2018

Cas1 and Cas2 From the Type II-C CRISPR-Cas System of

Yang He, Mingshu Wang, Mafeng Liu, Li Huang, Chaoyue Liu, Xin Zhang, Haibo Yi, Anchun Cheng, Dekang Zhu, Qiao Yang and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The core Cas1 protein of CRISPR-Cas I-B inCurrent research in microbial sciences · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. mSphere · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Yang HeInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mingshu WangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mafeng LiuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Li HuangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Chaoyue LiuKey Laboratory of Animal Diseases and Human Health of Sichuan Province, Chengdu, China.
Xin ZhangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Haibo YiInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Anchun ChengInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Dekang ZhuKey Laboratory of Animal Diseases and Human Health of Sichuan Province, Chengdu, China.
Qiao YangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ying WuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xinxin ZhaoInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shun ChenInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Renyong JiaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shaqiu ZhangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yunya LiuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yanling YuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ling ZhangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sichuan Agricultural University · CNNorth Sichuan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins provide acquired genetic immunity against the entry of mobile genetic elements (MGEs). The immune defense provided by various subtypes of the CRISPR-Cas system has been confirmed and is closely associated with the formation of immunological memory in CRISPR arrays, called CRISPR adaptation or spacer acquisition. However, whether type II-C CRISPR-Cas systems are also involved in spacer acquisition remains largely unknown. This study explores and provides some definitive evidence regarding spacer acquisition of the type II-C CRISPR-Cas system from

Indexed as

Adaptation, BiologicalBacterial ProteinsBase SequenceClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Associated ProteinsCRISPR-Cas SystemsDNA, BacterialEscherichia coliImmunityPlasmidsRiemerellaSequence DeletionBacterial ProteinsCRISPR-Associated ProteinsDNA, BacterialCas1Cas2CRISPR-CasRiemerella anatipestiferspacer acquisition

Identifiers

PMID29951376
PMCPMC6008519
OpenAlexW2807524305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.