Evidence map›Paper›PMID 29951281›Full record

ArticleNPJ vaccines2018

Long-term reduction in hyperglycemia in advanced type 1 diabetes: the value of induced aerobic glycolysis with BCG vaccinations.

Willem M Kühtreiber, Lisa Tran, Taesoo Kim, Michael Dybala, Brian Nguyen, Sara Plager, Daniel Huang, Sophie Janes, Audrey Defusco, Danielle Baum and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05591339 (Diabetes Diagnosis, Management, Prevention and Education in Guinea-Bissau), which is not on this map. Cited by 101 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 4 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05591339 phase4active not recruitingnot on this mapstarted 2023, after this paper: background citation

Diabetes Diagnosis, Management, Prevention and Education in Guinea-Bissau

TypeinterventionalSponsorBandim Health ProjectRan2023 to 2029Enrolled200ConditionsDiabetes Mellitus, BCG Vaccination ReactionArmsBCG vaccine (two doses, 4 weeks apart), Saline placebo (Two doses, 4 weeks apart)
3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 4 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Trial
  6. Immune boosting to combat Alzheimer's disease: Position statement.Journal of Alzheimer's disease : JAD · 2026
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Willem M Kühtreiber1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Lisa Tran1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Taesoo Kim1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Michael Dybala1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Brian Nguyen1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Sara Plager1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Daniel Huang1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.ORCID 0000-0003-2624-5439
Sophie Janes1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Audrey Defusco1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Danielle Baum1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Hui Zheng2Department of Biostatistics, Massachusetts General Hospital, Boston, MA 02115 USA.
Denise L Faustman1Immunobiology Laboratories, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th Street, Boston, MA 02116 USA.
Harvard University · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29951281
PMCPMC6013479
OpenAlexW2806126654

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.