Evidence map›Paper›PMID 29951221›Full record

ArticlePilot and feasibility studies2018

GeriMedRisk, a telemedicine geriatric pharmacology consultation service to address adverse drug events in long-term care: a stepped-wedge cluster randomized feasibility trial protocol (ISRCTN17219647).

Joanne Man-Wai Ho, Jennifer Tung, Janine Maitland, Derelie Mangin, Lehana Thabane, J Michael Pavlin, Jeffrey Alfonsi, Anne Holbrook, Sharon Straus, Sophiya Benjamin

Abstract read
In one paragraph

Article in Pilot and feasibility studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. [Interventions to optimise prescribing for older people in care homes].Zeitschrift fur Gerontologie und Geriatrie · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joanne Man-Wai Ho1Waterloo Regional Campus, McMaster University DeGroote School of Medicine, 10B Victoria St S, Kitchener, ON Canada.ORCID 0000-0002-8252-2034
Jennifer Tung3Grand River Hospital, 835 King St W, Kitchener, ON Canada.
Janine MaitlandSt. Joseph's Health Centre Guelph, 100 Westmount Ave, Guelph, ON Canada.
Derelie Mangin5Department of Family Medicine, McMaster University, 6th floor, 100 Main St W, Hamilton, ON Canada.
Lehana Thabane6Department of Health Research Methods, Evidence and Impact, McMaster University, H325, 50 Charlton Ave E, Hamilton, ON Canada.
J Michael Pavlin7Lazaridis School of Business and Economics, Wilfrid Laurier University, 64 University Ave W, Waterloo, ON Canada.
Jeffrey AlfonsiOntario Telemedicine Network, 1100-105 Moatfield Drive, Toronto, ON Canada.
Anne Holbrook6Department of Health Research Methods, Evidence and Impact, McMaster University, H325, 50 Charlton Ave E, Hamilton, ON Canada.
Sharon Straus10Li Ka Shing Knowledge Institute, St. Michael's Hospital, 30 Bond St Toronto, Toronto, ON Canada.
Sophiya Benjamin1Waterloo Regional Campus, McMaster University DeGroote School of Medicine, 10B Victoria St S, Kitchener, ON Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultimorbidity, polypharmacy, and older age predispose seniors to adverse drug events (ADE). Seniors with an ADE experience greater morbidity, mortality, and health care utilization compared to their younger counterparts. To mitigate and manage ADEs among this vulnerable population, we designed a geriatric pharmacology consultation service connecting clinicians with specialist physicians and pharmacists and will investigate the feasibility and acceptability of this complex intervention in the long-term care setting, prior to conducting a larger efficacy trial. METHODS/

designWe will conduct a cluster randomized feasibility trial and qualitative analysis of GeriMedRisk among four long-term care homes in the Waterloo-Wellington region from May 1 to December 31, 2017. The primary outcome is the feasibility and acceptability of GeriMedRisk and the stepped-wedge cluster randomized controlled trial design. We hypothesize that GeriMedRisk is a feasible intervention and its potential to decrease falls and drug-related hospital visits can be evaluated with a stepped-wedge cluster randomized controlled trial design. DISCUSSION: This mixed methods study will inform a larger efficacy trial of GeriMedRisk's ability to decrease adverse drug events among seniors in the long-term care setting. ETHICS AND DISSEMINATION: The Hamilton Integrated Research Ethics Board granted the approval for this study protocol 2812. We plan to disseminate the results of this study in peer-reviewed journals and also to our partners and stakeholders.

trial registrationISRCTN clinical trials registry, ISRCTN17219647 (March 27, 2017).

Indexed as

Appropriate prescribingClinical trialCluster randomized controlled trialFeasibilityGeriatricsTelemedicine

Identifiers

PMID29951221
PMCPMC6011190

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.