Evidence map›Paper›PMID 29951135›Full record

ReviewJournal of arrhythmia2018

Brugada syndrome and sinus node dysfunction.

Hidemori Hayashi, Masataka Sumiyoshi, Yuji Nakazato, Hiroyuki Daida

Open access · goldAbstract readReview
In one paragraph

Review in Journal of arrhythmia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Bradyarrhythmias and Brugada syndrome: clinical features, long-term outcome and prognostic implications-the BruBra study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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  5. A Tale of Two Conditions: Pediatric Brugada Syndrome Unveiled-Navigating the Challenges of Coexisting Arrhythmia and Fever-Induced ECG Pattern.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
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  15. Disease Modifiers of InheritedFrontiers in cardiovascular medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hidemori HayashiDepartment of Cardiovascular Medicine Juntendo University School of Medicine Tokyo Japan.
Masataka SumiyoshiDepartment of Cardiology Juntendo University Nerima Hospital Tokyo Japan.ORCID 0000-0002-2644-6356
Yuji NakazatoDepartment of Cardiology Juntendo University Urayasu Hospital Urayasu Japan.
Hiroyuki DaidaDepartment of Cardiovascular Medicine Juntendo University School of Medicine Tokyo Japan.
Juntendo University · JPJuntendo University Nerima Hospital · JPJuntendo University Urayasu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brugada syndrome (BrS) is a well-known catastrophic disease first reported in 1992 by the Brugada brothers. Ventricular fibrillation (VF) is an essential arrhythmia in BrS. An association between BrS and atrial tachyarrhythmias is not uncommon. However, sinus node dysfunction (SND) associated with BrS has not been well discussed. In this review, we focus on the association between BrS and SND. Based on previous reports describing clinical, epidemiological, and genetic evidence, SND is not a rare concomitant disorder in BrS. BrS may be a multiple conduction or arrhythmogenic disorder including not only the His-Purkinje system and right ventricle, but also the sinus node and atrium, derived from ion channel mutations.

Indexed as

Brugada syndromeoverlap syndromesick sinus syndromesinus node dysfunctionsodium channel mutation

Identifiers

PMID29951135
PMCPMC6009769
OpenAlexW2794518258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.