Evidence map›Paper›PMID 29951028›Full record

ArticleFrontiers in neurology2018

Topological Reorganization of the Default Mode Network in Severe Male Obstructive Sleep Apnea.

Liting Chen, Xiaole Fan, Haijun Li, Chenglong Ye, Honghui Yu, Honghan Gong, Xianjun Zeng, Dechang Peng, Liping Yan

Abstract read
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liting ChenDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Xiaole FanDepartment of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Haijun LiDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Chenglong YeDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Honghui YuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Honghan GongDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Xianjun ZengDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Dechang PengDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Liping YanDepartment of Cardiology, People's Hospital of Jiangxi Province, Nanchang, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired spontaneous regional activity and altered topology of the brain network have been observed in obstructive sleep apnea (OSA). However, the mechanisms of disrupted functional connectivity (FC) and topological reorganization of the default mode network (DMN) in patients with OSA remain largely unknown. We explored whether the FC is altered within the DMN and examined topological changes occur in the DMN in patients with OSA using a graph theory analysis of resting-state functional magnetic resonance imaging data and evaluated the relationship between neuroimaging measures and clinical variables. Resting-state data were obtained from 46 male patients with untreated severe OSA and 46 male good sleepers (GSs). We specifically selected 20 DMN subregions to construct the DMN architecture. The disrupted FC and topological properties of the DMN in patients with OSA were characterized using graph theory. The OSA group showed significantly decreased FC of the anterior-posterior DMN and within the posterior DMN, and also showed increased FC within the DMN. The DMN exhibited small-world topology in both OSA and GS groups. Compared to GSs, patients with OSA showed a decreased clustering coefficient (

Indexed as

cognitive functiondefault mode networkgraph theoryobstructive sleep apnearesting-state functional magnetic resonance imaging

Identifiers

PMID29951028
PMCPMC6008385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.