Evidence map›Paper›PMID 29950998›Full record

ArticleFrontiers in pharmacology2018

Mitochondrial Nicotinic Acetylcholine Receptors Support Liver Cells Viability After Partial Hepatectomy.

Kateryna Uspenska, Olena Lykhmus, Maria Obolenskaya, Stephanie Pons, Uwe Maskos, Serhiy Komisarenko, Maryna Skok

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  6. Mitochondria as a possible target for nicotine action.Journal of bioenergetics and biomembranes · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Kateryna UspenskaLaboratory of Cell Receptors Immunology, O. V. Palladin Institute of Biochemistry, Kiev, Ukraine.
Olena LykhmusLaboratory of Cell Receptors Immunology, O. V. Palladin Institute of Biochemistry, Kiev, Ukraine.
Maria ObolenskayaSystem Biology Group, Institute of Molecular Biology and Genetics, Kiev, Ukraine.
Stephanie PonsIntegrative Neurobiology of Cholinergic Systems, Institut Pasteur, Paris, France.
Uwe MaskosIntegrative Neurobiology of Cholinergic Systems, Institut Pasteur, Paris, France.
Serhiy KomisarenkoLaboratory of Cell Receptors Immunology, O. V. Palladin Institute of Biochemistry, Kiev, Ukraine.
Maryna SkokLaboratory of Cell Receptors Immunology, O. V. Palladin Institute of Biochemistry, Kiev, Ukraine.
Institut Pasteur · FRNational Academy of Sciences of Ukraine · UAPalladin Institute of Biochemistry · UAInstitute of Molecular Biology and Genetics · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types. The nAChRs expressed in mitochondria regulate the release of pro-apoptotic factors, like cytochrome

Indexed as

cytochrome cknockout micemitochondriamitochondrial kinasesnicotinic acetylcholine receptorpartial hepatectomy

Identifiers

PMID29950998
PMCPMC6008424
OpenAlexW2807738372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.