Evidence map›Paper›PMID 29950900›Full record

ArticleClinical epidemiology2018

Young patients with risk factors prevalent in the elderly - differences in comorbidity depending on severity of psoriasis: a nationwide cross-sectional study in Swedish health registers.

Mohammadhossein Hajiebrahimi, Marie Linder, David Hägg, Ina Anveden Berglind, Sean McElligott, Valgard Sverrir Valgardsson, Reginald Villacorta, Anders Sundström

Abstract read
In one paragraph

Article in Clinical epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Real-world study of direct medical and indirect costs and time spent in healthcare in patients with chronic graft versus host disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2021
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammadhossein HajiebrahimiCenter for Pharmacoepidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Marie LinderCenter for Pharmacoepidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
David HäggCenter for Pharmacoepidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Ina Anveden BerglindCenter for Pharmacoepidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Sean McElligottJanssen Research and Development, LLC, Horsham, PA, USA.
Valgard Sverrir ValgardssonJanssen-Cilag AS, Oslo, Norway.
Reginald VillacortaJanssen Research and Development, LLC, Horsham, PA, USA.
Anders SundströmCenter for Pharmacoepidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssociation between psoriasis severity and cerebro- and cardiovascular comorbidities has rarely been investigated.

aimWe aimed to investigate differences in cerebro- and cardiovascular comorbidities by psoriasis severity. MATERIALS AND

methodsUsing Swedish nationwide health-care registers, new adult users of anti-psoriatic drugs (2007-2013) with a recorded diagnosis of psoriasis/psoriatic arthritis or a filled prescription for calcipotriol were included. Psoriasis severity was based on the type of anti-psoriatic treatment (topical/mild, non-biologic systemic/moderate-to-severe, and biologics/ severe). Age standardized prevalence rates of cerebro- and cardiovascular comorbidities and their risk factors were compared between the groups.

resultsWe found that severe psoriasis patients (N=2147) were younger than moderate-to-severe (N=11,919) or mild (N=70,796) patients (median 44, 52, and 55 years). Prevalence of hypertension was 29.9%, 32.6%, and 36.5%, myocardial infarction was 2.5%, 2.3%, and 1.8%, and stroke was 2.4%, 2.2%, and 1.1% in mild, moderate-to-severe, and severe psoriasis patients, respectively. Diabetes prevalence was 7.6% in mild, 8.0% in moderate-to-severe, and 10.7% in severe psoriasis.

conclusionMyocardial infarction and stroke were less common in patients with severe psoriasis while, despite being younger, they had a higher prevalence of diabetes and hypertension.

Indexed as

cardiovascularcerebrovascularprevalencepsoriasisseverity

Identifiers

PMID29950900
PMCPMC6016015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.