Evidence map›Paper›PMID 29950877›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2018

Predictors of major lower limb amputation in type 2 diabetic patients referred for hospital care with diabetic foot syndrome.

Nawaf J Shatnawi, Nabil A Al-Zoubi, Hassan M Hawamdeh, Yousef S Khader, Khaled Garaibeh, Hussein A Heis

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03939000 (Clinical Profile and Laboratory Finding of Diabetic Foot Ulcers From Tertiary Hospitals in Bali), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03939000 completednot on this map

Clinical Profile and Laboratory Finding of Diabetic Foot Ulcers From Tertiary Hospitals in Bali

TypeobservationalSponsorUdayana UniversityRan2016 to 2019Enrolled113ConditionsDiabetic Foot Ulcer, Type 2 Diabetes Mellitus, Laboratory Problem, Physical Findings.Skin Ulcer
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  11. Elevated HbA1c level associated with disease severity and surgical extension in diabetic foot patients.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nawaf J ShatnawiDepartment of Surgery, Jordan University of Science and Technology, Irbid, Jordan.
Nabil A Al-ZoubiDepartment of Surgery, Jordan University of Science and Technology, Irbid, Jordan.
Hassan M HawamdehDepartment of Basic Medical Science, Jordan University of Science and Technology, Irbid, Jordan.
Yousef S KhaderDepartment of Community Medicine, Public Health and Family Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Khaled GaraibehDepartment of Orthopedic Surgery, Jordan University of Science and Technology, Irbid, Jordan.
Hussein A HeisDepartment of Surgery, Jordan University of Science and Technology, Irbid, Jordan.
Jordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was conducted to determine the risk factors of major lower extremity amputations in type 2 diabetic patients referred for hospital care with diabetic foot syndrome. PATIENTS AND

methodsThis retrospective study involved 225 type 2 diabetic patients referred for management of diabetic foot syndrome at King Abdullah University Hospital in the period between January 2014 and December 2015. A structured customized diabetic foot data collection form with diabetic foot characteristics chart was used for documentation of relevant information, which checks for age, sex, body mass index, smoking, duration of diabetes, diabetic control therapy, associated hypertension, cardiac diseases, stroke, chronic renal impairment, renal replacement therapy (hem-dialysis), and history of diabetes-related complication in both feet prior to the study period. The predictors for major lower limb amputations were compared between groups using chi-square test, and binary logistic regression was used to determine the factors associated with major amputation.

resultsTwenty-seven limbs underwent major amputations with an overall rate of major amputation of 11.6%. The following predictors were found to be associated with the higher incidence of major lower limb amputations: duration of diabetes ≥15 years, HbA1c ≥8%, patients on insulin, with hypertension, cardiac diseases, chronic renal impairment, stroke, having gangrene, higher number of components, higher Wagner classification, and ischemia. However, the rate did not differ significantly between men and women.

conclusionPresentation with gangrenous tissue and poor glycemic control are the important risks and significant predictive factors for type 2 diabetes-related major lower limb amputations.

Indexed as

amputationsdiabetes mellitusdiabetic foot complicationgangrene

Identifiers

PMID29950877
PMCPMC6018853
OpenAlexW2808877420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.