ReviewOncoTargets and therapy2018
Multiple biological functions of transcription factor 21 in the development of various cancers.
Review in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- TCF21-WNT5A axis drives metastasis of colorectal cancer via stromal-tumor cell communication.Journal of translational medicine · 2026Article
- Tcf21 modulates fibroblast activation and promotes cardiac fibrosis after injury via Pdgfrb signaling.Scientific reports · 2025Article
- AKAP12, mediated by transcription factor 21, inhibits cell proliferation, metastasis, and glycolysis in lung squamous cell carcinoma.Open life sciences · 2025Article
- Fibrosis and Hepatocarcinogenesis: Role of Gene-Environment Interactions in Liver Disease Progression.International journal of molecular sciences · 2024Review
- Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration.Nature communications · 2023Article
- Mechanism of TCF21 Downregulation Leading to Immunosuppression of Tumor-Associated Macrophages in Non-Small Cell Lung Cancer.Pharmaceutics · 2023Article
- Engineered modular heterocyclic-diamidines for sequence-specific recognition of mixed AT/GC base pairs at the DNA minor groove.Chemical science · 2021Article
- Upregulation of TCF21 inhibits migration of adrenocortical carcinoma cells.Discover oncology · 2021Article
- Genetic evaluation of the variants using MassARRAY in non-small cell lung cancer among North Indians.Scientific reports · 2021Article
- TCF21: a critical transcription factor in health and cancer.Journal of molecular medicine (Berlin, Germany) · 2020Review
- Analysis of genes associated with prognosis of lung adenocarcinoma based on GEO and TCGA databases.Medicine · 2020Article
- The Role of Transcription Factor 21 in Epicardial Cell Differentiation and the Development of Coronary Heart Disease.Frontiers in cell and developmental biology · 2020Review
- TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression.Genome medicine · 2019Article
- Small molecule binders recognize DNA microstructural variations via an induced fit mechanism.Physical chemistry chemical physics : PCCP · 2019Article
- Promoter methylation of the candidate tumor suppressor gene TCF21 in myelodysplastic syndrome and acute myeloid leukemia.American journal of translational research · 2019Article
- Compound Shape Effects in Minor Groove Binding Affinity and Specificity for Mixed Sequence DNA.Journal of the American Chemical Society · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcription factor 21 (TCF21) is a basic helix-loop-helix transcription factor that binds to DNA and regulates cell differentiation and cell fate specification through mesenchymal-epithelial transition during development. The
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.