Evidence map›Paper›PMID 29950689›Full record

ArticleScientific reports2018

A taxonomic signature of obesity in a large study of American adults.

Brandilyn A Peters, Jean A Shapiro, Timothy R Church, George Miller, Chau Trinh-Shevrin, Elizabeth Yuen, Charles Friedlander, Richard B Hayes, Jiyoung Ahn

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 7 pooled it
27.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

178 citing papers in PubMed, 7 syntheses or guidelines pooled it, 329 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Diet, adiposity, and the gut microbiota from infancy to adolescence: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  7. Gut microbiota phenotypes of obesity.NPJ biofilms and microbiomes
    Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Effect of Dietary Inulin Supplementation on the Gut Microbiota Composition and Derived Metabolites of Individuals Undergoing Hemodialysis: A Pilot Study.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2021
    Trial
  13. Integrative analysis of the intestinal metabolome of childhood asthma.The Journal of allergy and clinical immunology · 2019
    Trial
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

118 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Brandilyn A PetersDepartment of Population Health, New York University School of Medicine, New York, NY, USA.ORCID 0000-0002-1534-2578
Jean A ShapiroDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Timothy R ChurchDivision of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
George MillerDepartment of Surgery, New York University School of Medicine, New York, NY, USA.
Chau Trinh-ShevrinDepartment of Population Health, New York University School of Medicine, New York, NY, USA.
Elizabeth YuenKips Bay Endoscopy Center, New York, NY, USA.
Charles FriedlanderKips Bay Endoscopy Center, New York, NY, USA.
Richard B HayesDepartment of Population Health, New York University School of Medicine, New York, NY, USA.ORCID 0000-0002-0918-661X
Jiyoung AhnDepartment of Population Health, New York University School of Medicine, New York, NY, USA. Jiyoung.Ahn@nyumc.org.
New York University · USCenters for Disease Control and Prevention · USUniversity of Minnesota · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
The Oral Microbiome and Upper Aerodigestive Squamous Cell CancerR01CA159036 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AHN, JIYOUNG, HAYES, RICHARD BERNARD · 2011 to 2024
$3.5M
Oral microbiome in esophageal adenocarcinomaU01CA182370 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AHN, JIYOUNG, PEI, ZHIHENG · 2014 to 2018
$2.7M
Prospective Study of Human Oral Microbiome and Pancreatic Cancer RiskR01CA164964 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AHN, JIYOUNG · 2014 to 2017
$2.2M
Gut Microbiome Profiles and Risk of Colorectal CancerR03CA159414 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AHN, JIYOUNG, YANG, LIYING · 2012 to 2014
$219k
Fiber Intake, Gut Bacteria Metabolites and Risk of Colorectal CancerR21CA183887 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AHN, JIYOUNG · 2013 to 2013
$170k
NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA159036NCI NIH HHS R01 CA164964NCI NIH HHS R03 CA159414NCI NIH HHS R21 CA183887NCI NIH HHS U01 CA182370U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) P30CA016087U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R01CA159036U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R01CA164964U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R03CA159414U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R21CA183887U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) U01CA182370
6 · The paper itself

Abstract

Animal models suggest that gut microbiota contribute to obesity; however, a consistent taxonomic signature of obesity has yet to be identified in humans. We examined whether a taxonomic signature of obesity is present across two independent study populations. We assessed gut microbiome from stool for 599 adults, by 16S rRNA gene sequencing. We compared gut microbiome diversity, overall composition, and individual taxon abundance for obese (BMI ≥ 30 kg/m

Indexed as

AgedAged, 80 and overBody Mass IndexBody WeightCross-Sectional StudiesFecesFemaleGastrointestinal MicrobiomeHumansMaleMiddle AgedObesityRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID29950689
PMCPMC6021409
OpenAlexW2809642430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.