Evidence map›Paper›PMID 29950677›Full record

ArticleScientific reports2018

A novel high-throughput method for kinetic characterisation of anaerobic bioproduction strains, applied to Clostridium kluyveri.

Pieter Candry, Timothy Van Daele, Kyrina Denis, Youri Amerlinck, Stephen J Andersen, Ramon Ganigué, Jan B A Arends, Ingmar Nopens, Korneel Rabaey

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 79 citations in OpenAlex.

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  11. Why do lactic acid bacteria thrive in chain elongation microbiomes?Frontiers in bioengineering and biotechnology · 2023
    Article
  12. Article
  13. Review
  14. The potential of caproate (hexanoate) production usingFrontiers in bioengineering and biotechnology · 2022
    Article
  15. Reactor Designs and Configurations for Biological and Bioelectrochemical C1 Gas Conversion: A Review.International journal of environmental research and public health · 2021
    Review
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pieter CandryCenter for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Timothy Van DaeleBIOMATH, Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Kyrina DenisCenter for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Youri AmerlinckBIOMATH, Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Stephen J AndersenCenter for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Ramon GaniguéCenter for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Jan B A ArendsCenter for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.ORCID 0000-0001-7035-2587
Ingmar NopensBIOMATH, Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium.
Korneel RabaeyCenter for Microbial Ecology and Technology (CMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Gent, Belgium. Korneel.Rabaey@UGent.be.ORCID 0000-0001-8738-7778
Ghent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hexanoic acid (HA), also called caproic acid, can be used as an antimicrobial agent and as a precursor to various chemicals, such as fuels, solvents and fragrances. HA can be produced from ethanol and acetate by the mesophilic anaerobic bacterium Clostridium kluyveri, via two successive elongation steps over butyrate. A high-throughput anaerobic growth curve technique was coupled to a data analysis framework to assess growth kinetics for a range of substrate and product concentrations. Using this method, growth rates and several kinetic parameters were determined for C. kluyveri. A maximum growth rate (µ

Indexed as

Acetic AcidAnaerobiosisAnti-Infective AgentsButyric AcidCaproatesClostridium kluyveriEthanolKineticsAcetic AcidAnti-Infective AgentsButyric AcidCaproatesEthanolhexanoic acid

Identifiers

PMID29950677
PMCPMC6021416
OpenAlexW2809340185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.