Evidence map›Paper›PMID 29950577›Full record

ArticleScientific reports2018

Gp41 dynamically interacts with the TCR in the immune synapse and promotes early T cell activation.

Oren Yakovian, Roland Schwarzer, Julia Sajman, Yair Neve-Oz, Yair Razvag, Andreas Herrmann, Eilon Sherman

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Oren YakovianRacah Institute of Physics, The Hebrew University, Jerusalem, 91904, Israel.
Roland SchwarzerDepartment of Biology, Molecular Biophysics, Humboldt Universität zu Berlin, 10115, Berlin, Germany.ORCID 0000-0002-7497-5180
Julia SajmanRacah Institute of Physics, The Hebrew University, Jerusalem, 91904, Israel.
Yair Neve-OzRacah Institute of Physics, The Hebrew University, Jerusalem, 91904, Israel.
Yair RazvagRacah Institute of Physics, The Hebrew University, Jerusalem, 91904, Israel.
Andreas HerrmannDepartment of Biology, Molecular Biophysics, Humboldt Universität zu Berlin, 10115, Berlin, Germany.
Eilon ShermanRacah Institute of Physics, The Hebrew University, Jerusalem, 91904, Israel. sherman@phys.huji.ac.il.ORCID 0000-0002-7403-6036
Hebrew University of Jerusalem · ILHumboldt-Universität zu Berlin · DE

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) SFB 740Israel Science Foundation (ISF) 1417/13Israel Science Foundation (ISF) 1937/13
6 · The paper itself

Abstract

The HIV-1 glycoprotein gp41 critically mediates CD4

Indexed as

Cell LineHIV Envelope Protein gp41HumansLymphocyte ActivationMutationReceptors, Antigen, T-CellSoftwareSynapsesT-LymphocytesHIV Envelope Protein gp41Receptors, Antigen, T-Cell

Identifiers

PMID29950577
PMCPMC6021400
OpenAlexW2809088670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.