Evidence map›Paper›PMID 29950505›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

The Claudin-like Protein HPO-30 Is Required to Maintain LAChRs at the

Pallavi Sharma, Lei Li, Haowen Liu, Vina Tikiyani, Zhitao Hu, Kavita Babu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Microbiota-gut-brain axis and toll-like receptors in Alzheimer's disease.Computational and structural biotechnology journal · 2019
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pallavi SharmaDepartment of Biological Sciences, Indian Institute of Science Education and Research Mohali, Knowledge City, Punjab, India and.ORCID 0000-0002-6274-1846
Lei LiQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research, University of Queensland, St. Lucia, Queensland 4072, Australia.ORCID 0000-0002-6062-7097
Haowen LiuQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research, University of Queensland, St. Lucia, Queensland 4072, Australia.ORCID 0000-0001-8498-290X
Vina TikiyaniDepartment of Biological Sciences, Indian Institute of Science Education and Research Mohali, Knowledge City, Punjab, India and.ORCID 0000-0001-8533-1885
Zhitao HuQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research, University of Queensland, St. Lucia, Queensland 4072, Australia z.hu1@uq.edu.au kavitababu@iisermohali.ac.in kavita.babu@babulab.org.ORCID 0000-0002-2948-3339
Kavita BabuDepartment of Biological Sciences, Indian Institute of Science Education and Research Mohali, Knowledge City, Punjab, India and z.hu1@uq.edu.au kavitababu@iisermohali.ac.in kavita.babu@babulab.org.ORCID 0000-0002-7527-3666

Funding

WormBase: a core data resource for C. elegans and other nematodesU41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KERSEY, PAUL, SCHEDL, TIM · 2013 to 2017
$20.5M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
DBT-Wellcome Trust India Alliance IA/I/12/1/500516NHGRI NIH HHS U41 HG002223NIH HHS P40 OD010440Wellcome Trust
6 · The paper itself

Abstract

Communications across chemical synapses are primarily mediated by neurotransmitters and their postsynaptic receptors. There are diverse molecular systems to localize and regulate the receptors at the synapse. Here, we identify HPO-30, a member of the claudin superfamily of membrane proteins, as a positive regulator for synaptic localization of levamisole-dependent AChRs (LAChRs) at the

Indexed as

AldicarbAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsCell Adhesion Molecules, NeuronalDrug ResistanceExcitatory Postsynaptic PotentialsGene Expression RegulationGenes, ReporterLevamisoleMembrane ProteinsMotor ActivityMuscimolMusclesNeuromuscular JunctionAldicarbCaenorhabditis elegans ProteinsCarrier ProteinsCell Adhesion Molecules, Neuronalhpo-30 protein, C elegansLev-8 protein, C elegansLevamisoleMembrane ProteinsMuscimolneuroligin 1Receptors, NicotinicUNC-29 protein, C elegansUnc-38 protein, C elegansAChRsHPO-30levamisoleneuromuscular junction

Identifiers

PMID29950505
PMCPMC6083452

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.