Evidence map›Paper›PMID 29950349›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Therapeutic Immune Modulation against Solid Cancers with Intratumoral Poly-ICLC: A Pilot Trial.

Chrisann Kyi, Vladimir Roudko, Rachel Sabado, Yvonne Saenger, William Loging, John Mandeli, Tin Htwe Thin, Deborah Lehrer, Michael Donovan, Marshall Posner and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.

  1. A systematic review of ongoing clinical trials in optic pathway gliomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Innate immunity: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Ultrasound-guided intra-tumoral administration of directly-injected therapies: a review of the technical and logistical considerations.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Chrisann KyiTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Vladimir RoudkoTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Rachel SabadoTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Yvonne SaengerColumbia University Medical Center, New York, New York.
William LogingTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
John MandeliTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Tin Htwe ThinTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Deborah LehrerTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Michael DonovanTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Marshall PosnerTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Krzysztof MisiukiewiczTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Benjamin GreenbaumTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Andres SalazarOncovir, Inc., Washington, DC.
Philip FriedlanderTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Nina BhardwajTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York. Nina.Bhardwaj@mssm.edu.
Icahn School of Medicine at Mount Sinai · USColumbia University Irving Medical Center · USLabCorp (United States) · US

Funding

Modulating anti-HIV immunity by plasmacytoid dendritic cellsR01AI081848 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BHARDWAJ, NINA · 2010 to 2021
$4.5M
NK cell exhaustion in metastatic melanomaR01CA201189 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BHARDWAJ, NINA · 2016 to 2020
$2.1M
Matrix metalloproteinase-2 modulates inflammation via TLR2R01CA180913 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BHARDWAJ, NINA · 2014 to 2018
$1.8M
NCI NIH HHS R01 CA180913NCI NIH HHS R01 CA201189NIAID NIH HHS R01 AI081848
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedBiopsyCarboxymethylcellulose SodiumDrug Administration ScheduleFemaleGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansImmunohistochemistryImmunologic FactorsImmunomodulationInjections, IntralesionalKaplan-Meier EstimateMaleMiddle AgedNeoplasmsCarboxymethylcellulose SodiumImmunologic FactorsPoly I-Cpoly ICLCPolylysine

Identifiers

PMID29950349
PMCPMC6191332
OpenAlexW2809886276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.