Evidence map›Paper›PMID 29950348›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers.

Shahida Din, Kim Wong, Mike F Mueller, Anca Oniscu, James Hewinson, Catherine J Black, Martin L Miller, Alejandro Jiménez-Sánchez, Roy Rabbie, Mamunar Rashid and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Pathophysiology of colitis-associated colorectal cancer.Nature reviews. Gastroenterology & hepatology · 2026
    Review
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  19. Review
  20. Molecular characterization of ulcerative colitis-associated colorectal carcinomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Shahida Din *NHS Lothian, Gastrointestinal Unit, Western General Hospital, Edinburgh, Scotland, United Kingdom. sdin@ed.ac.uk.
Kim Wong *Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
Mike F MuellerDivision of Pathology, Centre for Comparative Pathology, Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, Scotland, United Kingdom.ORCID 0003-4972-6438
Anca OniscuNHS Lothian, Department of Molecular Pathology, Laboratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom.
James HewinsonWellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
Catherine J BlackNHS Lothian, Department of Pathology, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Martin L MillerCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom.ORCID 0003-3161-8690
Alejandro Jiménez-SánchezCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom.
Roy RabbieWellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.ORCID 0002-9195-5659
Mamunar RashidWellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
Jack SatsangiCentre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
David J AdamsWellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
Mark J ArendsDivision of Pathology, Centre for Comparative Pathology, Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, Scotland, United Kingdom.ORCID 0002-6826-8770
Wellcome Sanger Institute · GBEdinburgh Cancer Research · GBNHS Lothian · GBUniversity of Cambridge · GBUniversity of Edinburgh · GBWestern General Hospital · GB

Funding

Cancer Research UK 21141Cancer Research UK A21717Cancer Research UK A6997European Research Council 319661Wellcome Trust 082356Wellcome Trust 206194
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersMutationAllelesColorectal NeoplasmsDNA Copy Number VariationsDNA Mismatch RepairDNA Mutational AnalysisDNA Polymerase IIIEpitopesExome SequencingGene FrequencyHLA AntigensHumansInflammatory Bowel DiseasesMicrosatellite InstabilityMutation RateBiomarkersDNA Polymerase IIIEpitopesHLA AntigensPOLD1 protein, human

Identifiers

PMID29950348
PMCPMC6193541
OpenAlexW2810298079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.