Evidence map›Paper›PMID 29949870›Full record

ArticleInternational journal of environmental research and public health2018

Development of a Cumulative Exposure Index (CEI) for Manganese and Comparison with Bone Manganese and Other Biomarkers of Manganese Exposure.

Danelle Rolle-McFarland, Yingzi Liu, Jieqiong Zhou, Farshad Mostafaei, Yuanzhong Zhou, Yan Li, Quiyan Fan, Wei Zheng, Linda H Nie, Ellen M Wells

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. Article
  7. Characterization of bone aluminum, a potential biomarker of cumulative exposure, within an occupational population from Zunyi, China.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Danelle Rolle-McFarlandSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. Danelle.Rolle-Mcfarland@moffitt.org.
Yingzi LiuSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. yliu@wkhs.com.
Jieqiong ZhouSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. jieqiong.zhou@yale.edu.
Farshad MostafaeiSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. fmostafaei@mcw.edu.
Yuanzhong ZhouSchool of Public Health, Zunyi Medical University, Zunyi 563003, Guizhou, China. zhouyuanzhong@163.com.
Yan LiSchool of Public Health, Zunyi Medical University, Zunyi 563003, Guizhou, China. liyan067321@sina.com.
Quiyan FanZunyi Medical and Pharmaceutical College, Zunyi 563003, Guizhou, China. fanqy@zunyiyizhuan.cn.
Wei ZhengSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. wzheng@purdue.edu.
Linda H NieSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. hnie@purdue.edu.
Ellen M WellsSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. wells54@purdue.edu.ORCID 0000-0002-7293-1395
Purdue University West Lafayette · USZunyi Medical University · CNMedical College of Wisconsin · US

Funding

Choroid Plexus a Target in Metal-Induced NeurotoxicityR01ES008146 · NIEHS · PURDUE UNIVERSITY WEST LAFAYETTE · PI ZHENG, WEI · 1998 to 2014
$5.0M
Lead Exposure and Beta-Amyloid Transport by Brain BarriersR01ES027078 · NIEHS · PURDUE UNIVERSITY · PI DU, YANSHENG, ZHENG, WEI · 2017 to 2021
$2.2M
Moffitt Postdoctoral Training Program in Molecular EpidemiologyT32CA147832 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI KANETSKY, PETER A · 2015 to 2019
$659k
Bone Manganese as a Biomarker for Early Diagnosis of Manganese Neurotoxicity in OR21OH010700 · OH · PURDUE UNIVERSITY · PI NIE, LINDA H · 2014 to 2015
$401k
NCI NIH HHS T32 CA147832NIEHS NIH HHS R01 ES008146NIEHS NIH HHS R01 ES027078NIOSH CDC HHS R21 OH010700
6 · The paper itself

Abstract

Manganese (Mn) exposure can result in parkinsonism. However, understanding of manganese neurotoxicity has been limited by the lack of a cumulative Mn biomarker. Therefore, the current goal was to develop Mn cumulative exposure indices (MnCEI), an established method to estimate cumulative exposure, and determine associations of MnCEI with blood Mn (BMn), fingernail Mn (FMn), and bone Mn (BnMn). We completed a cross-sectional study of 60 male Chinese workers. Self-reported occupational history was used to create two MnCEIs reflecting the previous 16 years (MnCEI

Indexed as

AdultBiomarkersBone and BonesCross-Sectional StudiesHumansMaleManganeseManganese PoisoningMiddle AgedNailsOccupational ExposureBiomarkersManganesebiomarkersblood manganesebone manganesecumulative exposure indexfingernail manganesein vivo neutron activation analysismanganese

Identifiers

PMID29949870
PMCPMC6068959
OpenAlexW2810233297

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.