Evidence map›Paper›PMID 29949853›Full record

ArticleMarine drugs2018

Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium

Hanna Mazur-Marzec, Anna Fidor, Marta Cegłowska, Ewa Wieczerzak, Magdalena Kropidłowska, Marie Goua, Jenny Macaskill, Christine Edwards

Abstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Anabaenopeptins fromInternational journal of environmental research and public health · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Marine drugs · 2020
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanna Mazur-MarzecDivision of Marine Biotechnology, Faculty of Oceanography and Geography, University of Gdańsk, Marszałka J. Piłsudskiego 46, PL-81378 Gdynia, Poland. biohm@ug.edu.pl.ORCID 0000-0002-6526-4045
Anna FidorDivision of Marine Biotechnology, Faculty of Oceanography and Geography, University of Gdańsk, Marszałka J. Piłsudskiego 46, PL-81378 Gdynia, Poland. anna.fidor77@gmail.com.
Marta CegłowskaInstitute of Oceanology, Polish Academy of Sciences, Powstańców Warszawy 55, PL-81712 Sopot, Poland. mceglowska@iopan.pl.
Ewa WieczerzakDepartment of Biomedical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, PL-80308 Gdańsk, Poland. ewa.wieczerzak@ug.edu.pl.
Magdalena KropidłowskaDepartment of Biomedical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, PL-80308 Gdańsk, Poland. magdalena.kropidlowska@phdstud.ug.edu.pl.
Marie GouaSchool of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen AB10 7GJ, UK. m.goua@rgu.ac.uk.ORCID 0000-0003-1609-4366
Jenny MacaskillSchool of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen AB10 7GJ, UK. j.s.macaskill@rgu.ac.uk.ORCID 0000-0001-8200-0386
Christine EdwardsSchool of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen AB10 7GJ, UK. c.edwards@rgu.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanopeptolins (CPs) are one of the most frequently occurring cyanobacterial peptides, many of which are inhibitors of serine proteases. Some CP variants are also acutely toxic to aquatic organisms, especially small crustaceans. In this study, thirteen CPs, including twelve new variants, were detected in the cyanobacterium

Indexed as

Cell Line, TumorChymotrypsinCyanobacteriaHumansInhibitory Concentration 50MCF-7 CellsNostocPancreatic ElastasePeptides, CyclicProtein Phosphatase 1Tandem Mass SpectrometryThrombinTrypsinTrypsin InhibitorsChymotrypsinPancreatic ElastasePeptides, CyclicProtein Phosphatase 1ThrombinTrypsinTrypsin InhibitorscyanobacteriacyanopeptolinsNostocprotease inhibitors

Identifiers

PMID29949853
PMCPMC6070996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.