ArticleAllergy, asthma & immunology research2018
High Prevalence of Asthma in Elderly Women: Findings From a Korean National Health Database and Adult Asthma Cohort.
Article in Allergy, asthma & immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 55 citations in OpenAlex.
- The nationwide retrospective cohort study by Health Insurance Review and Assessment Service proves that asthma management decreases the exacerbation risk of asthma.Scientific reports · 2021Trial
- Impact of comorbid asthma on severity of coronavirus disease (COVID-19).Scientific reports · 2020Trial
- Socioeconomic, Behavioural, and Environmental Determinants of Asthma Inequalities in Europe: A Cross-Sectional Study Using EHIS Data.International journal of environmental research and public health · 2026Article
- Development and validation of a long-term survival prediction model for older adults with asthma.Archives of public health = Archives belges de sante publique · 2026Article
- Distribution of Allergy Diagnoses and Cardiometabolic Comorbidities Among Older Adults with EHR-Recorded Allergic Diseases - A Single-Center Retrospective Study.Journal of asthma and allergy · 2025Article
- Association between preterm birth and asthma and atopic dermatitis in preschool children: a nationwide population-based study.European journal of pediatrics · 2024Article
- A brief overview of SARS-CoV-2 infection and its management strategies: a recent update.Molecular and cellular biochemistry · 2024Review
- Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents.Allergy, asthma & immunology research · 2024Article
- Characteristics of Severe Asthma in the Elderly: Observations From the Korean Severe Asthma Registry (KoSAR).Allergy, asthma & immunology research · 2024Article
- Chinese expert consensus on the diagnosis, treatment, and management of asthma in women across life.Journal of thoracic disease · 2024Review
- Flow cytometry profiling of cellular immune response in COVID-19 infected, recovered and vaccinated individuals.Immunobiology · 2023Article
- Epidemiology of patients with asthma in Korea: Analysis of the NHISS database 2006-2015.The World Allergy Organization journal · 2023Article
- Interleukin-4 (C590T) Gene Polymorphism in Association with Asthma Severity.Journal of asthma and allergy · 2023Article
- Characteristics and difference of respiratory diseases in Korean adults aged ≥40 years: A cross-sectional study.The clinical respiratory journal · 2023Article
- Effect of Dupilumab in Korean Patients With Uncontrolled Moderate-to-Severe Asthma: A LIBERTY ASTHMA QUEST Sub-analysis.Allergy, asthma & immunology research · 2022Article
- Pomegranate extract supplementation improves lung function parameters and IL-35 expression in participants with mild and moderate persistent allergic asthma: A randomized, double-blind, placebo-controlled trial.Frontiers in nutrition · 2022Article
- A nationwide survey of the association between nonalcoholic fatty liver disease and the incidence of asthma in Korean adults.PloS one · 2022Article
- Exacerbation ofVirulence · 2021Article
- Long-Term Prognosis of Asthma-Bronchiectasis Overlapped Patients: A Nationwide Population-Based Cohort Study.Allergy, asthma & immunology research · 2021Article
- The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19.International immunopharmacology · 2021Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe prevalence and burden of asthma is increasing worldwide. In this study, we analyzed 3 different Korean national health survey datasets to determine the general features of adult asthma in Korea and to obtain basic information that would support future strategies for better management of adult asthma.
methodsThe surveys used in this study included the Korea National Health and Nutrition Examination Survey (KNHANES), Korea Community Health Survey (KCHS) and National Health Insurance Service-National Sample Cohort (NHIS-NSC). We investigated annual asthma prevalence, evaluating the rate and risk factors of asthma exacerbation by age and sex, and clinical data of 1,832 patients with asthma who were registered in the Cohort for Reality and Evolution of Adult Asthma in Korea (COREA) were analyzed to elucidate risk factors for asthma exacerbation. We also analyzed another asthma cohort and added it as replication data.
resultsIn the KNHANES database, annual asthma prevalence rates varied from 1.2% to 3.1%. In the KCHS database, overall prevalence increased, with significant regional differences (1.6%-2.1%). The NHIS-NSC indicated a gradual increase in annual asthma prevalence from 4.5% to 6.2%. Interestingly, all 3 surveys indicated the highest prevalence of asthma among elderly women. In addition, elderly women with asthma had a significantly higher risk of asthma exacerbation (odds ratio [OR], 1.87; 95% confidence interval [CI], 1.19-2.93; P=0.006). Approximately 11% of patients were classified as having severe asthma. An asthma cohort analysis identified female sex, low baseline pulmonary function, longer treatment duration, high variability in pulmonary function and significant changes in Asthma Control Test scores as risk factors for asthma exacerbation.
conclusionsThe prevalence of asthma in Korea is consistently high among elderly and female populations. These results should lay the foundation for strategies for effective asthma prevention and management; elderly female patients with asthma should receive particular attention.
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