Evidence map›Paper›PMID 29949771›Full record

ArticleCell reports2018

Synchronized Astrocytic Ca

Xiaochun Gu, Wei Chen, Nora D Volkow, Alan P Koretsky, Congwu Du, Yingtian Pan

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 78 citations in OpenAlex.

  1. Prolonged systemic inflammation worsens impairments to astrocyte CaAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
  4. Low frequency BOLD oscillations,medRxiv : the preprint server for health sciences · 2025
    Article
  5. Review
  6. Review
  7. Prolonged systemic inflammation worsens impairments to astrocyte CabioRxiv : the preprint server for biology · 2025
    Article
  8. Astrovascular decoupling in awake 5×FAD mice is associated with reduced astrocytic calcium.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Article
  10. Article
  11. Neurophotonics · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Astrocyte Regulation of Cerebral Blood Flow in Health and Disease.Cold Spring Harbor perspectives in biology · 2024
    Review
  19. Review
  20. Astrocytic GPCR-Induced CaInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Xiaochun GuDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA; Jiangsu Key Laboratory of Molecular and Functional Imaging, Key Laboratory of Developmental Genes and Human Diseases, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, #87 Dingjiaqiao Road, Nanjing 210009, China.
Wei ChenDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.
Nora D VolkowNational Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20857, USA.
Alan P KoretskyLaboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.
Congwu DuDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.
Yingtian PanDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address: yingtian.pan@stonybrook.edu.
Stony Brook University · USNational Institute of Neurological Disorders and Stroke · USNational Institute on Alcohol Abuse and Alcoholism · US

Funding

Neurobiology of Substance Abuse and AddictionZIAAA000550 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI VOLKOW, NORA D. · 2009 to 2025
$115.1M
Functional Imaging of The BrainZIANS002989 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI KORETSKY, ALAN · 2009 to 2025
$41.5M
Calcium-related Neurotoxicity of CocaineR01DA029718 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI DU, CONGWU, PAN, YINGTIAN · 2012 to 2025
$4.2M
Optical platform to image neuronal and vascular effects of cocaine in awake rodentsR21DA042597 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI DU, CONGWU, PAN, YINGTIAN · 2016 to 2017
$392k
Ultrahigh-resolution optical tomography of cocaine-induced neurovascular toxicityR21DA032228 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI DU, CONGWU, PAN, YINGTIAN · 2011 to 2012
$388k
NIDA NIH HHS R01 DA029718NIDA NIH HHS R21 DA032228NIDA NIH HHS R21 DA042597
6 · The paper itself

Abstract

The role of astrocytes in neurovascular coupling (NVC) is unclear. Here, we applied a multimodality imaging approach to concomitantly measure synchronized neuronal or astrocytic Ca

Indexed as

Neurovascular CouplingAnimalsAstrocytesCalciumElectric StimulationMiceMice, TransgenicNeuronsSomatosensory CortexTime-Lapse ImagingVasoconstrictionCalciumastrocyteastrocytic Ca(2+) fluctuationGCaMP6flow-frequency oscillationsneuronneurovascular couplingresting statesomatosensory stimulationsynchronized astrocyte responsessynchronized neuronal responses

Identifiers

PMID29949771
PMCPMC7469112
OpenAlexW2811091313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.