ReviewAnnual review of psychology2019
Ten Surprising Facts About Stressful Life Events and Disease Risk.
Review in Annual review of psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 242 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
242 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Maternal Experiences of Stressful Life Events and Its Association With Teenage Pregnancy and Preterm Birth: A Systematic Review and Meta-Analysis.Trauma, violence & abuse · 2026Pooled it
- An update meta-analysis on the relationship between psychotic experiences and self-injurious thoughts and behaviors in children and adolescents.European child & adolescent psychiatry · 2025Pooled it
- Stressful life events as precipitants of obsessive-compulsive disorder: a systematic review and meta-analysis.CNS spectrums · 2025Pooled it
- The effects of stress on reward responsiveness: a systematic review and preliminary meta-analysis of the event-related potential literature.Cognitive, affective & behavioral neuroscience · 2024Pooled it
- The Impact of Psychosocial Stress from Life Trauma and Racial Discrimination on Epigenetic Aging-A Systematic Review.Biological research for nursing · 2022Pooled it
- Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis.BMC biology · 2022Pooled it
- Evaluating a brief smartphone-based stress management intervention with heart rate biofeedback from built-in sensors in a three arm randomized controlled trial.Scientific reports · 2025Trial
- Trial
- Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial.Scientific reports · 2024Trial
- The effectiveness of the Wim Hof method on cardiac autonomic function, blood pressure, arterial compliance, and different psychological parameters.Scientific reports · 2023Trial
- The Dynamics of Daily Life in Custodial Grandmothers.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Trial
- Trial
- Stressor-elicited smoking and craving during a smoking cessation attempt.Journal of psychopathology and clinical science · 2022Trial
- Adolescent mental health in Hong Kong: a longitudinal analysis of positive self-evaluation, contextual influences and adverse experiences (2009-2014).Child and adolescent mental health · 2026Article
- Nonlinear Dose-Response Association Between Stressful Life Events and Probable Problematic Internet Use Among Chinese College Students: Cross-Sectional Study.Journal of medical Internet research · 2026Article
- Changes in toothbrushing and factors associated with less than twice daily toothbrushing by the age of four in the FinnBrain Birth Cohort Study.Acta odontologica Scandinavica · 2026Article
- Associations Between Virtual Prenatal Care Utilization, Social Determinants of Health, and Stressful Life Events: A Multistate Analysis of U.S. Women, 2020-2021.Maternal and child health journal · 2026Article
- Stress-induced IL-6 response patterns amplify the link between daily negative affect and later depressive symptoms during bereavement.Brain, behavior, and immunity · 2026Article
- Negative affect and peripheral inflammation: The role of cognitive reappraisal and expressive suppression.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Toward next-generation stress generation research: Expert consensus methodological guidelines.Journal of psychopathology and clinical science · 2026Article
182 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
After over 70 years of research on the association between stressful life events and health, it is generally accepted that we have a good understanding of the role of stressors in disease risk. In this review, we highlight that knowledge but also emphasize misunderstandings and weaknesses in this literature with the hope of triggering further theoretical and empirical development. We organize this review in a somewhat provocative manner, with each section focusing on an important issue in the literature where we feel that there has been some misunderstanding of the evidence and its implications. Issues that we address include the definition of a stressful event, characteristics of diseases that are impacted by events, differences in the effects of chronic and acute events, the cumulative effects of events, differences in events across the life course, differences in events for men and women, resilience to events, and methodological challenges in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.