Evidence map›Paper›PMID 29949674›Full record

ArticleCancer science2018

Transcriptional repression of human epidermal growth factor receptor 2 by ClC-3 Cl

Mayu Fujimoto, Hiroaki Kito, Junko Kajikuri, Susumu Ohya

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Translational cancer research · 2024
    Article
  6. Article
  7. Review
  8. Role of ANO1 in tumors and tumor immunity.Journal of cancer research and clinical oncology · 2022
    Review
  9. Review
  10. Review
  11. The CaActa pharmaceutica Sinica. B · 2021
    Review
  12. The Prognostic Value and Mechanisms of TMEM16A in Human Cancer.Frontiers in molecular biosciences · 2021
    Review
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mayu FujimotoDepartment of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Kyoto, Japan.
Hiroaki KitoDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Junko KajikuriDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Susumu OhyaDepartment of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-5765-0667
Kyoto Pharmaceutical University · JPNagoya City University · JP

Funding

JSPS KAKENHI JP16K08285
6 · The paper itself

Abstract

Recent studies have indicated that the intracellular concentration of chloride ions (Cl

Indexed as

Gene Expression Regulation, NeoplasticAnoctamin-1Breast NeoplasmsCell Line, TumorChloride ChannelsChloridesErb-b2 Receptor Tyrosine KinasesFemaleHistonesHumansNeoplasm ProteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionSTAT3 Transcription FactorTOR Serine-Threonine KinasesANO1 protein, humanAnoctamin-1Chloride ChannelsChloridesClC-3 channelERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesHistonesMTOR protein, humanNeoplasm ProteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSTAT3 protein, humanSTAT3 Transcription FactorTOR Serine-Threonine KinasesAKTbreast cancerClC-3HER2STAT3

Identifiers

PMID29949674
PMCPMC6125433
OpenAlexW2810823441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.