SynthesisPloS one2018
Should kissing balloon inflation after main vessel stenting be routine in the one-stent approach? A systematic review and meta-analysis of randomized trials.
Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06822322 (The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations - EBC DCB Study), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations - EBC DCB Study
Who cites it
20 citing papers in PubMed.
- Impact of stent size selection during a single stenting with kissing balloon inflation for left main bifurcation lesions.Cardiovascular intervention and therapeutics · 2026Article
- Design of IKISS-LM Randomized Controlled Trial: Impact of Kissing Balloon Inflation on Provisional Left-Main Bifurcation PCI.JACC. Asia · 2026Article
- Advancements in Coronary Bifurcation Stenting Techniques: Insights From Computational and Bench Testing Studies.International journal for numerical methods in biomedical engineering · 2025Review
- Review of Techniques for Protecting Side Branch from Occlusion during Provisional Stenting in Coronary Bifurcation Lesions.Reviews in cardiovascular medicine · 2023Review
- Novel application of drug-coated balloons in coronary heart disease: A narrative review.Frontiers in cardiovascular medicine · 2023Review
- Coronary Bifurcation Stenting: Review of Current Techniques and Evidence.Current cardiology reviews · 2023Review
- Longitudinal outcomes of final kissing balloon inflation in coronary bifurcation lesions treated with a single stent.Frontiers in cardiovascular medicine · 2023Article
- Evaluation of Long-Term Outcomes of Crossover or Focal Ostial Stenting of Left Anterior Descending Artery Ostial Stenosis.Anatolian journal of cardiology · 2022Article
- Left Main Coronary Artery Disease-Current Management and Future Perspectives.Journal of clinical medicine · 2022Review
- Treatment of coronary bifurcation lesions, part I: implanting the first stent in the provisional pathway. The 16th expert consensus document of the European Bifurcation Club.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
- Percutaneous coronary intervention of bifurcation lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
- Fundamentals of percutaneous coronary bifurcation interventions.World journal of cardiology · 2022Review
- How to use three-dimensional optical coherence tomography effectively in coronary bifurcation stenting.Frontiers in cardiovascular medicine · 2022Review
- The importance of experimental models in interventional cardiology. An illustration in coronary bifurcation stenting.Cardiology journal · 2022Article
- Practice Patterns in the Interventional Treatment of Coronary Bifurcation Lesions: A Global Survey.The Journal of invasive cardiology · 2022Article
- Provisional Stenting for the Treatment of Bifurcation Lesions: In Vitro Insights.Journal of cardiovascular translational research · 2021Article
- 5-Year Outcome of Simple Crossover Stenting in Coronary Bifurcation Lesions Compared With Side Branch Opening.JACC. Asia · 2021Article
- Percutaneous coronary intervention for bifurcation coronary lesions: the 15EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
- Comparison of diagnostic performance in assessing the rewiring position into a jailed side branch between online 3D reconstruction systems version 1.1 and 1.2 derived from optical frequency domain imaging.Cardiovascular intervention and therapeutics · 2020Article
- Percutaneous Coronary Intervention for Coronary Bifurcation Lesions: Latest Evidence.Current treatment options in cardiovascular medicine · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The KBI (kissing balloon inflation) technique is considered the default strategy for the two-stent approach in real world practice. Studies comparing KBI and No-KBI in patients undergoing the one-stent approach have reported conflicting results. The meta-analysis was performed to compare the clinical outcomes of the KBI strategy and the No-KBI strategy for coronary bifurcation lesions in the one-stent approach. Five randomized studies were included, and a total of 1264 patients were involved in the meta-analysis. The primary outcome was cardiac death. The secondary end points were stent thrombosis, MI (myocardial infarction), target lesion revascularization (TLR), target vessel revascularization (TVR), and main vessel and side branch restenosis. Compared with the No-KBI strategy, the KBI strategy was associated with a significant reduction in side branch restenosis (OR: 0.44, 95% CI: 0.30-0.64, p<0.001). A high risk of main vessel restenosis was found in the KBI group (OR: 2.96, 95% CI: 1.74-5.01, p<0.001). There were no significant differences in rates of cardiac death (OR: 1.89, 95% CI: 0.60-5.95, p = 0.28), stent thrombosis (OR: 0.98, 95% CI: 0.19-4.94, p = 0.98), MI (OR: 0.68, 95% CI: 0.33-1.44, p = 0.30), TLR (OR 1.14, 95% CI 0.68-1.90, p = 0.62), or TVR (OR 1.27, 95% CI 0.75-2.16, p = 0.38). Compared with the No-KBI strategy, the KBI strategy reduced the incidence of side branch restenosis and increased the risk of main branch restenosis in the one-stent approach. However, the clinical outcomes were similar between the KBI and No-KBI groups.
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