Evidence map›Paper›PMID 29949419›Full record

ReviewAJR. American journal of roentgenology2018

Imaging Prostate Cancer With Prostate-Specific Membrane Antigen PET/CT and PET/MRI: Current and Future Applications.

Thomas A Hope, Ali Afshar-Oromieh, Matthias Eiber, Louise Emmett, Wolfgang P Fendler, Courtney Lawhn-Heath, Steven P Rowe

Open access · greenAbstract readReview
In one paragraph

Review in AJR. American journal of roentgenology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Meta-analysis ofCancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Automated radiosynthesis of [Journal of labelled compounds & radiopharmaceuticals · 2021
    Article
  10. Prospective Evaluation ofAJR. American journal of roentgenology · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Accuracy ofAmerican journal of nuclear medicine and molecular imaging · 2020
    Article
  15. Review
  16. Article
  17. Novel Structured Reporting Systems for Theranostic Radiotracers.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Review
  18. A Festschrift in Honor of Edward M. Messing, MD, FACS.Bladder cancer (Amsterdam, Netherlands) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Thomas A Hope1 Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628.
Ali Afshar-Oromieh4 Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland.
Matthias Eiber6 Department of Nuclear Medicine, Klinikum Rechts der Isar, Technical University of Munich, Germany.
Louise Emmett7 Department of Diagnostic Imaging, St. Vincent's Public Hospital, Sydney, Australia.
Wolfgang P Fendler10 Klinik für Nuklearmedizin, Universitätsklinikum, Essen, Germany.
Courtney Lawhn-Heath1 Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628.
Steven P Rowe11 The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
University of California, San Francisco · USJohns Hopkins University · USKlinik und Poliklinik für Nuklearmedizin · DESt Vincent's Hospital Sydney · AUUniversity Hospital Heidelberg · DE

Funding

Qualification and Harmonization of PET/MRI for Cancer Clinical TrialsR01CA212148 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOPE, THOMAS, LAFOREST, RICHARD ANDRE · 2017 to 2022
$2.7M
NCI NIH HHS R01 CA212148
6 · The paper itself

Abstract

objectiveThe purpose of this article is to describe the large number of radiotracers being evaluated for prostate-specific membrane antigen (PSMA) PET, which is becoming a central tool in the staging of prostate cancer.

conclusionPSMA PET is a highly promising modality for the staging of prostate cancer because of its higher detection rate compared with that of conventional imaging. Both PET/CT and PET/MRI offer benefits with PSMA radiotracers, and PSMA PET findings frequently lead to changes in management. It is imperative that subsequent treatment changes be evaluated to show improved outcomes. PSMA PET also has potential applications, including patient selection for PSMA-based radioligand therapy and evaluation of treatment response.

Indexed as

Magnetic Resonance ImagingMultimodal ImagingPositron Emission Tomography Computed TomographyBiomarkers, TumorHumansMaleNeoplasm StagingPatient SelectionProstate-Specific AntigenProstatic NeoplasmsBiomarkers, TumorProstate-Specific AntigenPETPET/MRIprostate cancerprostate-specific membrane antigen

Identifiers

PMID29949419
PMCPMC7001912
OpenAlexW2811198550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.