ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018
Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Sulfur(VI) Fluoride Exchange Chemistry in Polymer Functionalization: Post-Polymerization Modification, Interface Engineering, and Biopolymer Conjugation.Molecules (Basel, Switzerland) · 2026Review
- Disubstituted Meldrum's Acid: Another Scaffold with SuFEx-like Reactivity.Molecules (Basel, Switzerland) · 2025Article
- Click Chemistry for Biofunctional Polymers: From Observing to Steering Cell Behavior.Chemical reviews · 2024Review
- Sulfur-Phenolate Exchange as a Mild, Fast, and High-Yielding Method toward the Synthesis of Sulfonamides.Organic letters · 2023Article
- Sulfur-Phenolate Exchange As a Fluorine-Free Approach to S(VI) Exchange Chemistry on Sulfonyl Moieties.Organic letters · 2022Article
- Clickable Polysaccharides for Biomedical Applications: A Comprehensive Review.Progress in polymer science · 2022Article
- Sulfur-Phenolate Exchange: SuFEx-Derived Dynamic Covalent Reactions and Degradation of SuFEx Polymers.Angewandte Chemie (International ed. in English) · 2022Article
- Configurationally Chiral SuFEx-Based Polymers.Angewandte Chemie (International ed. in English) · 2022Article
- Sulfonyl fluorides as targets and substrates in the development of new synthetic methods.Nature reviews. Chemistry · 2022Review
- Accelerated SuFEx Click Chemistry For Modular Synthesis.Angewandte Chemie (International ed. in English) · 2022Article
- SuFExable polymers with helical structures derived from thionyl tetrafluoride.Nature chemistry · 2021Article
- Oxidation-Induced "One-Pot" Click Chemistry.Chemical reviews · 2021Article
- A Unified Strategy for Arylsulfur(VI) Fluorides from Aryl Halides: Access to Ar-SOFAngewandte Chemie (International ed. in English) · 2020Article
- Complementary Base Lowers the Barrier in SuFEx Click Chemistry for Primary Amine Nucleophiles.ACS omega · 2020Article
- Cycloaddition of Strained Cyclic Alkenes andThe Journal of organic chemistry · 2020Article
- Silicon-Free SuFEx Reactions of Sulfonimidoyl Fluorides: Scope, Enantioselectivity, and Mechanism.Angewandte Chemie (International ed. in English) · 2020Article
- SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Functionalization at Will of Rim-Differentiated Pillar[5]arenes.Organic letters · 2019Article
- Strain-Promoted Cycloaddition of Cyclopropenes with o-Quinones: A Rapid Click Reaction.Angewandte Chemie (International ed. in English) · 2018Article
- Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The constraints of minute reactant amounts and the impossibility to remove any undesired surface-bound products during monolayer functionalization of a surface necessitate the selection of efficient, modular and orthogonal reactions that lead to quantitative conversions. Herein, we explore the character of sulfur-fluoride exchange (SuFEx) reactions on a surface, and explore the applicability for quantitative and orthogonal surface functionalization. To this end, we demonstrate the use of ethenesulfonyl fluoride (ESF) as an efficient SuFEx linker for creating "SuFEx-able" monolayer surfaces, enabling three distinct approaches to utilize SuFEx chemistry on a surface. The first approach relies on a di-SuFEx loading allowing dual functionalization with a nucleophile, while the two latter approaches focus on dual (CuAAC-SuFEx/SPOCQ-SuFEx) click platforms. The resultant strategies allow facile attachment of two different substrates sequentially on the same platform. Along the way we also demonstrate the Michael addition of ethenesulfonyl fluoride to be a quantitative surface-bound reaction, indicating significant promise in materials science for this reaction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.