ArticleCognitive, affective & behavioral neuroscience2018
Functional connectivity of reflective and brooding rumination in depressed and healthy women.
Article in Cognitive, affective & behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Comparative meta-analysis of task-related functional brain abnormalities in nonsuicidal self-injury and suicide attempt.Frontiers in psychiatry · 2026Pooled it
- Meta-analytic evidence that mindfulness training alters resting state default mode network connectivity.Scientific reports · 2022Pooled it
- Change in Resting-State Functional Connectivity Following Working Memory Training in Individuals With Repetitive Negative Thinking.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Trial
- Reduced task-switching flexibility in parietal-cingulate and frontal circuits associated with brooding.Cognitive neurodynamics · 2026Article
- Differences in brain functional connectivity between autonomous sensory meridian response and classical music.Frontiers in neuroscience · 2026Article
- Shared but distinct functional connectome profiles underlying rumination in depressed and healthy individuals.BMC psychiatry · 2025Article
- Reduced mind-wandering and fewer depressive symptoms associated with damage to the medial prefrontal cortex and default mode network.Neuropsychologia · 2025Article
- Functional brain network dynamics of brooding in depression: Insights from real-time fMRI neurofeedback.Journal of affective disorders · 2025Article
- Multivariate Neural Markers of Individual Differences in Thought Control Difficulties.bioRxiv : the preprint server for biology · 2025Article
- Ambivalence-dependent alterations in brain function during self-evaluation in adults with depressive symptoms.Social cognitive and affective neuroscience · 2025Article
- Rumination and psychological resilience in Chinese civil aviation flight students: the chain mediating role of proactive coping and generalized anxiety disorder.Frontiers in psychology · 2025Article
- Multivariate neural markers of individual differences in thought control difficulties.NeuroImage. Clinical · 2025Article
- Transcriptional patterns of amygdala functional connectivity in first-episode, drug-naïve major depressive disorder.Translational psychiatry · 2024Article
- Functional brain network dynamics of brooding in depression: insights from real-time fMRI neurofeedback.medRxiv : the preprint server for health sciences · 2024Article
- Functional connectivity of the amygdala subregions and the antidepressant effects of repeated ketamine infusions in major depressive disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Aberrant degree centrality profiles during rumination in major depressive disorder.Human brain mapping · 2023Article
- Trait repetitive negative thinking in depression is associated with functional connectivity in negative thinking state rather than resting state.Journal of affective disorders · 2023Article
- Rumination mediates the relationship between childhood trauma and depressive symptoms in schizophrenia patients.European archives of psychiatry and clinical neuroscience · 2023Article
- Trait repetitive negative thinking in depression is associated with functional connectivity in negative thinking state rather than resting state.bioRxiv : the preprint server for biology · 2023Article
- A Semantic Cognition Contribution to Mood and Anxiety Disorder Pathophysiology.Healthcare (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ruminative thinking is related to an increased risk for major depressive disorder (MDD) and perpetuates negative mood states. Rumination, uncontrollable negative thoughts about the self, may comprise both reflective and brooding components. However, only brooding rumination is consistently associated with increased negativity bias and negative coping styles, while reflective rumination has a less clear relationship with negative outcomes in healthy and depressed participants. The current study examined seed-to-voxel (S2.V) resting-state functional connectivity (FC) in a sample of healthy (HC) and depressed (MDD) adult women (HC: n=50, MDD: n=33). The S2V FC of six key brain regions, including the left and right amygdala, anterior and posterior cingulate cortex (ACC, PCC), and medial and dorsolateral prefrontal cortices (mPFC, dlPFC), was correlated with self-reported reflective and brooding rumination. Results indicate that HC and MDD participants had increased brooding rumination associated with decreased FC between the left amygdala and the right temporal pole. Moreover, reflective rumination was associated with distinct FC of the mPFC, PCC, and ACC with parietal, occipital, and cingulate regions. Depressed participants, compared with HC, exhibited decreased FC between the PCC and a region in the right middle frontal gyrus. The results of the current study add to the understanding of the neural underpinnings of different forms of self-related cognition-brooding and reflective rumination-in healthy and depressed women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.