Evidence map›Paper›PMID 29949055›Full record

ArticleJournal of the American Society for Mass Spectrometry2018

Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry.

Anne L Bruinen, Gregory L Fisher, Rachelle Balez, Astrid M van der Sar, Lezanne Ooi, Ron M A Heeren

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Methods for Cryosectioning and Mass Spectrometry Imaging of Whole-Body Zebrafish.Journal of the American Society for Mass Spectrometry · 2020
    Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Anne L BruinenM4i, The Maastricht Multi Modal Molecular Imaging Institute, Maastricht University, 6229 ER, Maastricht, The Netherlands.
Gregory L FisherPhysical Electronics, Inc., Chanhassen, MN, 55317, USA.
Rachelle BalezIllawarra Health and Medical Research Institute, School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia.
Astrid M van der SarVU University Medical Center Medical Microbiology and Infection control, 1081 HV, Amsterdam, The Netherlands.
Lezanne OoiIllawarra Health and Medical Research Institute, School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia.
Ron M A HeerenM4i, The Maastricht Multi Modal Molecular Imaging Institute, Maastricht University, 6229 ER, Maastricht, The Netherlands. r.heeren@maastrichtuniversity.nl.
Maastricht University · NLAmsterdam UMC Location VUmc · NLIllawarra Health and Medical Research Institute · AUUniversity of Wollongong · AU

Funding

European Molecular Biology Organization Short term fellowshipNational Health and Medical Research Council APP1135720Provincie Limburg LINK ProgramStichting voor de Technische Wetenschappen OTP 11956
6 · The paper itself

Abstract

A unique method for identification of biomolecular components in different biological specimens, while preserving the capability for high speed 2D and 3D molecular imaging, is employed to investigate cellular response to oxidative stress. The employed method enables observing the distribution of the antioxidant α-tocopherol and other molecules in cellular structures via time-of-flight secondary ion mass spectrometry (TOF-SIMS (MS

Indexed as

alpha-TocopherolAnimalsCells, CulturedFishesHumansImaging, Three-DimensionalInduced Pluripotent Stem CellsMaleMiddle AgedMolecular ImagingNeuronsTandem Mass SpectrometryWhole Body ImagingZebrafishalpha-TocopherolMass spectrometry imagingTandem MSTOF-SIMSVitamin Eα-tocopherol

Identifiers

PMID29949055
PMCPMC6060986
OpenAlexW2808042627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.