ArticleNeurocritical care2018
Combination of Clinical Exam, MRI and EEG to Predict Outcome Following Cardiac Arrest and Targeted Temperature Management.
Article in Neurocritical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prediction of poor outcome after hypoxic-ischemic brain injury by diffusion-weighted imaging: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Utility of magnetic resonance spectroscopy in predicting favorable outcome in adult comatose patients following cardiac arrest.Resuscitation · 2025Article
- Quantitative and Radiological Assessment of Post-cardiac-Arrest Comatose Patients with Diffusion-Weighted Magnetic Resonance Imaging.Neurocritical care · 2025Article
- Early Burst Suppression Similarity Association with Structural Brain Injury Severity on MRI After Cardiac Arrest.Neurocritical care · 2025Article
- Background EEG Suppression Ratio for Early Detection of Cerebral Injury in Pediatric Cardiac Arrest.Neurocritical care · 2024Article
- Neuroimaging in Disorders of Consciousness and Recovery.Physical medicine and rehabilitation clinics of North America · 2024Review
- Combination strategy for prognostication in patients undergoing post-resuscitation care after cardiac arrest.Scientific reports · 2023Article
- Prognosis of consciousness disorders in the intensive care unit.Presse medicale (Paris, France : 1983) · 2023Review
- Free water corrected diffusion tensor imaging discriminates between good and poor outcomes of comatose patients after cardiac arrest.European radiology · 2023Article
- Parieto-Occipital Injury on Diffusion MRI Correlates with Poor Neurologic Outcome following Cardiac Arrest.AJNR. American journal of neuroradiology · 2023Article
- Applications of Advanced MRI to Disorders of Consciousness.Seminars in neurology · 2022Review
- Predicting Neurological Outcome From Electroencephalogram Dynamics in Comatose Patients After Cardiac Arrest With Deep Learning.IEEE transactions on bio-medical engineering · 2022Article
- Magnetic resonance imaging adds prognostic value to EEG after pediatric cardiac arrest.Resuscitation · 2022Observational
- Regional Distribution of Brain Injury After Cardiac Arrest: Clinical and Electrographic Correlates.Neurology · 2022Article
- MRI markers of brain network integrity relate to neurological outcome in postanoxic coma.NeuroImage. Clinical · 2022Article
- Predicting neurological outcome in comatose patients after cardiac arrest with multiscale deep neural networks.Resuscitation · 2021Article
- Critical care EEG standardized nomenclature in clinical practice: Strengths, limitations, and outlook on the example of prognostication after cardiac arrest.Clinical neurophysiology practice · 2021Review
- MRI in disorders of consciousness.Current opinion in neurology · 2020Review
- MRI-EEG correlation for outcome prediction in postanoxic myoclonus: A multicenter study.Neurology · 2020Article
- Neuron-specific enolase and neuroimaging for prognostication after cardiac arrest treated with targeted temperature management.PloS one · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the widespread adoption of targeted temperature management (TTM), coma after cardiac arrest remains a common problem with a high proportion of patients suffering substantial disability. Prognostication after cardiac arrest, particularly the identification of patients with likely good outcome, remains difficult.
methodsWe performed a retrospective study of 78 patients who underwent TTM after cardiac arrest and were evaluated with both electroencephalography (EEG) and magnetic resonance imaging (MRI). We hypothesized that combining malignant versus non-malignant EEG classification with clinical exam and quantitative analysis of apparent diffusion coefficient (ADC) and fluid-attenuated inversion recovery imaging would improve prognostic ability.
resultsConsistent with prior literature, presence of a malignant EEG pattern was 100% specific for poor outcome. We found that decreased whole brain ADC signal intensity was associated with poor outcome (853 ± 14 vs. 950 ± 17.5 mm
conclusionWe conclude that in the absence of malignant EEG findings, combination of physical exam and MRI findings can be a useful to identify those patients who have potential for recovery. Variability in timing of imaging and findings in different modalities argue for the need for future prospective studies of multimodal outcome prediction after cardiac arrest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.