Evidence map›Paper›PMID 29949003›Full record

Observational studyNeurocritical care2018

Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral Hemorrhage.

Cora H Ormseth, Guido J Falcone, Sara D Jasak, David M Mampre, Audrey C Leasure, Laura C Miyares, David Y Hwang, Michael L James, Fernando D Testai, Kyra J Becker and 4 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Neurocritical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Palliative care after stroke: A review.International journal of stroke : official journal of the International Stroke Society · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Race, Socioeconomic Status, and Gastrostomy after Spontaneous Intracerebral Hemorrhage.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020
    Observational
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Cora H OrmsethDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
Guido J FalconeDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
Sara D JasakDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
David M MampreDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
Audrey C LeasureDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
Laura C MiyaresDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
David Y HwangDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA.
Michael L JamesDepartments of Anesthesiology and Neurology, Duke University, Durham, USA.
Fernando D TestaiDepartments of Neurology and Rehabilitation, University of Illinois at Chicago, Chicago, USA.
Kyra J BeckerDepartment of Neurology, University of Washington, Seattle, USA.
David L TirschwellDepartment of Neurology, University of Washington, Seattle, USA.
Carl D LangefeldDivision of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, USA.
Daniel WooDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, USA.
Kevin N ShethDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, 15 York Street, LLCI Room 1003C, New Haven, CT, 06510, USA. kevin.sheth@yale.edu.
Yale University · USDuke University · USSeattle University · USUniversity of Cincinnati · USUniversity of Illinois Chicago · USUniversity of Washington · USWake Forest University · US

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
NIA NIH HHS P30 AG021342NINDS NIH HHS U-01-NS069763NINDS NIH HHS U01 NS069763
6 · The paper itself

Abstract

backgroundPrior studies of patients in the intensive care unit have suggested racial/ethnic variation in end-of-life decision making. We sought to evaluate whether race/ethnicity modifies the implementation of comfort measures only status (CMOs) in patients with spontaneous, non-traumatic intracerebral hemorrhage (ICH).

methodsWe analyzed data from the Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study, a prospective cohort study specifically designed to enroll equal numbers of white, black, and Hispanic subjects. ICH patients aged ≥ 18 years were enrolled in ERICH at 42 hospitals in the USA from 2010 to 2015. Univariate and multivariate logistic regression analyses were implemented to evaluate the association between race/ethnicity and CMOs after adjustment for potential confounders.

resultsA total of 2705 ICH cases (912 black, 893 Hispanic, 900 white) were included in this study (mean age 62 [SD 14], female sex 1119 [41%]). CMOs patients comprised 276 (10%) of the entire cohort; of these, 64 (7%) were black, 79 (9%) Hispanic, and 133 (15%) white (univariate p < 0.001). In multivariate analysis, compared to whites, blacks were half as likely to be made CMOs (OR 0.50, 95% CI 0.34-0.75; p = 0.001), and no statistically significant difference was observed for Hispanics. All three racial/ethnic groups had similar mortality rates at discharge (whites 12%, blacks 9%, and Hispanics 10%; p = 0.108). Other factors independently associated with CMOs included age (p < 0.001), premorbid modified Rankin Scale (p < 0.001), dementia (p = 0.008), admission Glasgow Coma Scale (p = 0.009), hematoma volume (p < 0.001), intraventricular hematoma volume (p < 0.001), lobar (p = 0.032) and brainstem (p < 0.001) location and endotracheal intubation (p < 0.001).

conclusionsIn ICH, black patients are less likely than white patients to have CMOs. However, in-hospital mortality is similar across all racial/ethnic groups. Further investigation is warranted to better understand the causes and implications of racial disparities in CMO decisions.

Indexed as

AdultAgedBlack or African AmericanCerebral HemorrhageFemaleHispanic or LatinoHumansMaleMiddle AgedPalliative CarePatient ComfortProspective StudiesUnited StatesWhite PeopleWithholding TreatmentEnd-of-life careIntracerebral hemorrhageRace and ethnicity

Identifiers

PMID29949003
PMCPMC6286261
OpenAlexW2806002520

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.