Evidence map›Paper›PMID 29948993›Full record

Observational studyIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2018

Prevalence of celiac disease among pediatric patients with cryptogenic cirrhosis and effect of gluten-free-diet.

Ashish Joshi, Sushil Falodia, Naveen Kumar, Pawan Gupta, P C Khatri

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashish JoshiDepartment of Gastroenterology, Sardar Patel Medical College, Bikaner, 334 001, India.
Sushil FalodiaDepartment of Gastroenterology, Sardar Patel Medical College, Bikaner, 334 001, India.
Naveen KumarDepartment of General Medicine, Sardar Patel Medical College, Bikaner, 334 001, India. naveengoudamv@gmail.com.ORCID http://orcid.org/0000-0002-6748-3188
Pawan GuptaDepartment of Pediatrics, Sardar Patel Medical College, Bikaner, 334 001, India.
P C KhatriDepartment of Pediatrics, Sardar Patel Medical College, Bikaner, 334 001, India.
Sardar Patel Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver involvement in celiac disease (CD) is classified into autoimmune and cryptogenic. The association between CD and autoimmune liver diseases like autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis is well-established; however, the data on patients with cryptogenic cirrhosis, particularly from India, are scanty. So we did this study to find the prevalence of CD in patients with cryptogenic cirrhosis.

methodsThis was a prospective observational study, involving children of less than 18 years old attending Pediatric and Gastroenterology clinic with a diagnosis of cryptogenic cirrhosis. The patients were evaluated for CD and divided into two groups: chronic liver disease (CLD) with CD, and CLD without CD. Both the groups were followed up for 6 months. CLD with CD group was treated with gluten-free-diet (GFD) and CLD without CD group was followed up without any specific intervention except standard care of CLD.

resultsOut of 84 patients, 11 (13.1%) were diagnosed as CLD with CD. There was an improvement in hemoglobin levels, liver function tests, and Child-Pugh score after initiation of GFD in CLD with CD group.

conclusionThe prevalence of CD in cryptogenic cirrhosis was 13.1%. Screening for CD is recommended for cryptogenic cirrhosis. Hepatic functions improve with a GFD in CD patients with cirrhosis.

Indexed as

Diet, Gluten-FreeAdolescentCeliac DiseaseChildChild, PreschoolChronic DiseaseFemaleHumansInfantLiver CirrhosisMalePrevalenceProspective StudiesCeliac diseaseChild-Pugh scoreCryptogenic cirrhosisGluten-free-diet

Identifiers

PMID29948993
OpenAlexW2807777151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.