ReviewCurrent reviews in musculoskeletal medicine2018
Two-Stage Revision Arthroplasty for the Treatment of Prosthetic Joint Infection.
Review in Current reviews in musculoskeletal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Diagnostic accuracy of positron emission tomography/computerized tomography for periprosthetic joint infection of hip: systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Acute kidney injury in the context of staged revision arthroplasty and the use of antibiotic-laden cement spacers: a systematic review.Journal of orthopaedic surgery and research · 2023Pooled it
- Incidence, associated factors, and outcomes of acute kidney injury following placement of antibiotic bone cement spacers in two-stage exchange for periprosthetic joint infection: a comprehensive study.Frontiers in cellular and infection microbiology · 2023Pooled it
- Impact of surface structuring on antibiotic elution from bone cement in two-stage revision for periprosthetic joint infection.BMC musculoskeletal disorders · 2026Article
- Predictors of Failure After Two-Stage Revision for Periprosthetic Joint Infections of the Knee.Arthroplasty today · 2026Article
- Clinical and psychosocial impact of limited mobility during the interstage period of two-stage revision arthroplasty for prosthetic joint infection: a state-of-the-art review.Journal of orthopaedic surgery and research · 2026Review
- Quantification of Vancomycin and Clindamycin in Synovial Tissue and Bone Using Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry.Therapeutic drug monitoring · 2026Article
- Radiographic parameters and mechanical complications of articulating vs. non-articulating hip spacers.Archives of orthopaedic and trauma surgery · 2026Article
- Six-Week Protocol for Two-Stage Exchange Arthroplasty in a High-Risk Population.Arthroplasty today · 2026Article
- Combined use of 18 F-FDG PET/CT and MRI for evaluating infection status and clinical outcomes before reimplantation in two-stage revision arthroplasty.Journal of orthopaedic surgery and research · 2026Article
- Application of a new lavage-suction technique in managing chronic periprosthetic joint infection : Short running title: new lavage-section technique for PJI.Journal of orthopaedic surgery and research · 2025Article
- The effect of pulsatile lavage on antibiotic elution from bone cements in two-stage revision for periprosthetic joint infection.Journal of orthopaedic surgery and research · 2025Article
- Results of Aspiration, Erythrocyte Sedimentation Rate, and C-Reactive Protein in Patients With Known Prosthetic Joint Infection on Chronic Suppression.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Threaded rods versus arthrodesis nail as a static spacer for two-stage revision total knee arthroplasty.Archives of orthopaedic and trauma surgery · 2025Article
- Local Antimicrobial Potential of Bupivacaine and Tolfenamic Acid-Loaded Ultra-High Molecular Weight Polyethylene (UHMWPE) for Orthopedic Infection.Bioengineering (Basel, Switzerland) · 2025Article
- Safety of vancomycin-loaded cement spacers for treating gram-positive periprosthetic joint infections in two-stage resection arthroplasty among patients with renal insufficiency.BMC musculoskeletal disorders · 2025Article
- Effect of novel antimicrobial blue light-emitting optical fiber on vancomycin-resistantJournal of bone and joint infection · 2025Article
- Short-term follow-up of antibiotic-loaded calcium sulfate in treating chronic periprosthetic joint infection during two-stage revision.Frontiers in bioengineering and biotechnology · 2025Article
- Antibiotic-loaded cement in total joint arthroplasty: a comprehensive review.Archives of orthopaedic and trauma surgery · 2024Review
- Long-term Survival of Hip Cement Spacer: A Case Report.Revista brasileira de ortopedia · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo review the diagnosis and treatment of prosthetic joint infection (PJI) with a focus on two-stage revision arthroplasty. The text will discuss different spacer constructs in total knee and total hip arthroplasty and will present clinical outcome data for these various options. RECENT
findingsThere is no appreciable difference in infection eradication between mobile and static antibiotic spacers. Mobile spacers have shown improved knee range of motion after second-stage re-implantation. Two-stage revision arthroplasty is the gold standard treatment for PJI. The first stage involves removal of all components, cement, and compromised soft tissues with placement of an antibiotic-impregnated spacer. Spacer options include both mobile and static spacers. Mobile spacers offer maintenance of ambulation and joint range of motion between staged procedures and have shown to be as effective in eradicating infection as static spacers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.